PREFACE XI 



of this knowledge to the prophylaxis, diagnosis, and treatment of many 

 of the diseases to which these animals are subject. I have, therefore, 

 included in this volume an account of those immunologic diagnostic 

 reactions and applications of specific therapy that have a direct bearing 

 upon veterinary medicine. 



No attempt has been made to cover all literature references on the 

 subject. An effort has been made to state well-established facts con- 

 cisely, and, in the case of the more recent subjects, to give the principal 

 references to the literature. I have drawn largely from German' 

 French, and English sources, and have endeavored, wherever possible, 

 to give proper and due credit to each author. In order to keep the work 

 up to the times, I would ask the authors of reprints on immunologic 

 subjects to send me copies. 



The illustrations, all of which have been made by Mr. Erwin F. 

 Faber, will, it is hoped, serve the purpose for which they are intended, 

 namely, to elucidate the text and to teach, rather than merely to em- 

 bellish. 



It is with deep and sincere appreciation that I acknowledge the en- 

 couragement and aid given me by Professor Allen J. Smith, who has 

 written the introduction and reviewed several chapters. My thanks 

 are also due to Professor Richard M. Pearce for reviewing the chapters 

 on Infection; to my assistant, Dr. Anna M. Raiziss, for a number of 

 translations from foreign literature, and to the publishers, whose kind 

 and unvarying courtesy has greatly simplified the work. 



J. A. K. 



MCMANES LABORATORY OF EXPERIMENTAL PATHOLOGY, 

 UNIVERSITY OF PENNSYLVANIA, January, 1915. 



