642 



ACTIVE IMMUNIZATION 



is followed by redness and induration in the subcutaneous tissues, but 

 abscesses are never formed. 



Cases of severe injury, such as deep bites about the face and fingers, 

 should be rapidly immunized (intensive treatment)} in other cases the 

 treatment may be mild (mild treatment). The uniform dose of cord 

 emulsion, prepared as just described, is 2.5 c.c. The series of inocula- 

 tions given in the Research Laboratory of New York in treating human 

 cases after an average bite are as follows: 



TABLE 23. SCHEDULE OF INOCULATIONS IN IMMUNIZATION 



AGAINST RABIES 



Results. According to reliable statistics, the mortality of rabies 

 without the Pasteur treatment is about 16 per cent.; with the treat- 

 ment the average mortality is about 0.46 per cent. The mortality of 

 those bitten about the face or head is about 1.25 per cent.; of those 

 bitten on the hand, 0.75 per cent. ; of those bitten on other parts of the 

 body, a little over 0.25 to 1 per cent. In the Pasteur Institute of Paris 

 only such persons are treated as have been lacerated, so that the virus 

 has gained entry into the wounds. Taking into consideration only 

 those cases in which the diagnosis of rabies has been confirmed in the 

 animal by a competent examiner, the mortality of the cases treated at 

 the Pasteur Institute in Paris is only 0.6 per cent., which, compared to 

 the average mortality of 16 per cent, without vaccine treatment, speaks 

 most favorably for the value of Pasteur's antirabic immunization. 



