800 



CHEMOTHERAPY 



or bears a 300 c.c. mark; with 0.6 gm. in solution, each 50 c.c. contain 

 0.1 gm., so that thetdose given may be controlled by the amount of fluid 

 injected. This flask is thoroughly shaken to insure an even diffusion 

 of the drug, and the contents poured into thp cylinder from which it is 

 administered, being filtered into this cylinder through a piece of sterile 

 gauze in order to remove any bits of broken glass from the ampule that 

 may have gained access or any other insoluble particles. (See Fig. 142.) 



FIG. 142. INTRAVENOUS INJECTION OF SALVARSAN. 



With this apparatus the operator may give an injection without assistance. 

 Notice the three-way cock, which permits the flow of salt solution or salvarsan solu- 

 tion at will. Usually a tourniquet composed of a simple rubber tubing and held in 

 position byahemostat is better than the one shown, as the operator can quickly re- 

 lease it with least disturbance and loss of time. Note the funnels in both con- 

 tainers for straining the salvarsan solution and distilled water or salt solution. (After 

 the apparatus of Boehm.) 



Preparation of Neosalvarsan Solution. This drug is readily soluble 

 in water, forming a clear solution which is ready for use. File the neck 

 of the ampule, cleanse it with alcohol, and break open. The contents 

 are emptied directly into a flask containing 200 c.c. of warm, sterile, 

 freshly distilled water. On gentle agitation the drug rapidly dissolves. 

 Hot water should not be used, nor should a solution be heated once it has 

 been made. From the mixing flasks the solution is poured into the 

 cylinder through a piece of sterile gauze, which filters out any bits of 



