PART V 



EXPERIMENTAL INFECTION AND IMMUNITY 



INTRODUCTORY 



Methods. The exercises and experiments herein outlined are for 

 the purpose of teaching the principles of infection and immunity by 

 actual laboratory work, whereby the student performs the experiments 

 and is taught to observe the results. At the same time a knowledge 

 of the technic of immunologic methods is obtained. The instructor in 

 charge of such an experimental course may choose certain experiments 

 in outlining a course according to the allotment of tune and purpose of 

 the instruction. 



In all instances I have outlined the experiments according to average 

 conditions. It is readily understood that differences in the virulence of 

 a certain culture or the weight and physical condition of an experimental 

 animal will require that the doses advised be changed to meet the condi- 

 tions. 



As a general rule, a course should be concentrated, with exercises at 

 least three times a week in order that the student may follow his work 

 closely and have an opportunity for making adequate and accurate ob- 

 servations. 



An attempt is made to bring out the important points of an experi- 

 ment by a few pertinent questions. It should be impressed upon the 

 student that the mind should be held open for observation and that un- 

 expected and untoward results may be obtained which, however, are 

 always of interest and always instructive when the experiment is con- 

 ducted in a careful, methodical, and conscientious manner. Frequent 

 general discussions should be held for a general review of the subject and 

 correlation of facts and observations. In my experience students are 

 eager for the work and seldom fail to suggest additional work in the 

 nature of original research. 



The Student. 1. The student should work protected by an apron 

 or gown with short sleeves; he should be careful of the hands and avoid 

 abrasions and cuts and carefully wash and disinfect the hands after the 

 work of each day has been completed. 



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