878 



INDEX 



Diphtheria antitoxin, production of, 227 

 collecting serum, 230 

 immunizing animals, 228 

 rectal method of administering, 707 

 sequels, 712 



serum sickness from, 712 

 standardizing, 23 1 



experimental work, 835 

 subcutaneous injection, 707 

 total amount to be administered, 712 

 treatment of relapses with, 712 

 unit of, 242 

 value, 713 

 bacillus, 112 



virulence and toxicity, method of 



testing, 818 

 Behring's method of immunization 



against, 717 



nasal, dosage of antitoxin in, 710 

 nature of, 704 



of eye, dosage of antitoxin in, 711 

 of vulva, dosage of antitoxin in, 711 

 of wounds, dosage of antitoxin in, 711 

 prophylactic immunization against, 



715 



serum treatment, 702. See also Diph- 

 theria antitoxin. 



tonsillar, dosage of antitoxin in, 710 

 toxin, 112 



experimental work, 817 

 limes death dose, 232 



zero dose, 232 



method of testing virulence, 113 

 production of, 227 

 standardizing, 114 

 testing, 228 

 toxoid, 115 



treatment of, 704. See also Diph- 

 theria antitoxin. 

 Diplococcus pneumonise, 755 

 Disease, antiferments in, 247 

 bacteriolytic serums in treatment of, 



359 

 diagnosis of, Pfeiffer bacteriolytic test 



348 



ferments in, 248 

 Pfeiffer's bacteriolytic test in diagnosis 



of, 348 



production of, 107 

 sero-enzymes in, 264 

 Dixon's tuberculin, dose of, 675 



preparation, 667 

 Dog, anaphylaxis in, 540 

 intravenous inoculation, 62 

 obtaining large amounts of blood from, 



51 



small amount of blood from, 51 

 Donath and Landsteiner's method of 

 serum diagnosis of paroxysmal hemo- 

 globinuria, 379 

 Dose, intoxicating, 536 

 Dourine, complement-fixation test in, 



487 



Drug fastness, 789 

 idiosyncrasy, 578 



Duhring's disease, salvarsan in, 811 

 Dungern's complement-fixation test in 



cancer, 500 

 modification of Wassermann reaction, 



459 



Dysentery, agglutination test in, 276 

 antitoxin, 730 



administration and uses, 730 

 serum treatment, 730 



results, 731 

 toxin, 116 



experimental work, 820 

 vaccination, 652 



EAR, tuberculosis of, tuberculin test in 



diagnosis of, 590 

 treatment, 679 



Echinococcus disease, complement-fixa- 

 tion test in, 492 

 miostagmin reaction in, 530 

 Effusions, non-tuberculous, autoserum 



treatment, 782 



Egg-albumen idiosyncrasy, 578 

 Ehrlich's method of serum diagnosis of 



paroxysmal hemoglobinuria, 379 

 theory of immunity, 146 



and Metchnikoff s theory, com- 

 patibility, 155 



therapia magna sterilisans, 791 

 Electric centrifuge, 18 

 Emulsion, bacterial, in opsonic index, 194 

 Emulsions, 511 

 Endemic infection, 82 

 Endocarditis, antistreptococcus serum in, 



764 



ulcerative, vaccine therapy, 661 

 Endocellular complement, 330 

 Endocomplement, 330 

 Endogenous infection, 85, 86 

 Endolysins, 183, 339 

 Endotpxic substances, method of ob- 

 taining, 121 



Endotoxins, 108, 120, 182 

 as anaphylactogens, 548 

 experimental work, 823 

 influence of bacteriolysins on, 340 

 method of obtaining, 121 

 nature of, 121 



Enteritis anaphylactica, 540 

 Enzootic infection, 82 

 Enzymes, 244 



sero-, in disease, 264. See also Sero- 

 enzymes. 



Eosin-selenium compound in cancer, 812 

 Epidemic cerebrospinal meningitis, treat- 

 ment, 738 

 infection, 82 

 Epiphanin reaction, 522 

 in cancer, 526 

 in malignant disease, 526 

 in pregnancy, 526 

 in sarcoma, 526 

 in syphilis, 526 

 principle, 522 



