886 



INDEX 



Noguchi's modification of Wassermann 



reaction, 449 

 antigen for, 453 



titration of, 453 

 complement for, 450 

 experimental work, 859 

 fluid to be tested, 455 

 hemolytic amboceptor for, 451 

 human corpuscles for, 451 

 technic, 450 

 test, 455 



Nolf's theory of anaphylaxis, 558 

 Nucleoproteins, production of, 74 

 NuttalTs method of obtaining large 

 amount of blood from rabbit, 42 



OPHTHALMIC mallein, preparation, 607 



reaction, 607 



reaction in typhoid fever, 608 

 Opsonic index, 191 



as diagnostic procedure, 204 



as guide to size and frequency of 



doses of bacterial vaccines, 205 

 bacterial emulsion in, 194 

 collection of patient's and control 



serum, 193 

 definition, 191 



determining, experimental work, 834 

 in prognosis, 204 

 limitation, 192 

 practical value, 203 

 precautions in technic, 193 

 principle, 191 

 purpose, 192 

 technic, 193 



precautions in, 193 

 washed leukocytes in, 195 

 Opsonification, susceptibility to, 189 

 Opsonins, 145, 185, 187 



action of, mechanism, experimental 



work, 832 

 definition of, 188 

 effect of, on bacteria, 189 

 experimental work, 815, 831 

 history of, 187 

 immune, experimental work, 832 



production of, 69 

 in immunity, 190 

 nature of, 188 



normal, experimental work, 831 

 properties of, 188 

 source of, 189 



specificity of, experimental work, 833 

 Oral method of administering diphtheria 



antitoxin, 707 



route for tuberculin treatment, 676 

 Organotropism, 785 

 Osmotic pressure of colloids, 512 

 O. T. tuberculin, dose of, 674 



preparation of, 664 

 Otitis media, vaccine therapy, 660 

 Overproduction theory of Weigert, 148 

 Overwork as predisposing to disease, 100 



PALTAUF'S theory of mechanism of 

 agglutination, 270 



Pandemic infection, 82 



Paradox of Kretz, 548 



Paralysis, general, Wassermann reaction 

 in, 462 



Paralytic dementia, Wassermann reac- 

 tion in, 462 



Parasites, 83 



animal, aggressiveness of, 133 

 infection with, 132 



modes, 132 



production of disease by, 133 

 half, 124 

 partial, 124 

 true, 124 



Parasitotropism, 785 



Parasyphilitic diseases, Wassermann re- 

 action in, 462 



Paratyphoid fever, miostagmin reaction 

 in, 530 



Paroxysmal hemoglobinuria, serum diag- 

 nosis, 379 



Pasteur on immunity, 141, 142 

 treatment of rabies, intensive, 642 

 mild, 642 

 principle, 640 

 results, 642 



Pasteurian vaccination, 171 



Pearce's method of producing nephro- 

 toxic serum, 73 



Pellagra, salvarsan in, 811 

 Wassermann reaction in, 466 



Pelvic tuberculosis, tuberculin test in 

 diagnosis of, 590 



Percutaneous tuberculin test of Moro, 

 587, 599 



Peritonitis, tuberculous, tuberculin 'test 

 in diagnosis of, 591 



Pertussis, vaccine therapy, 659 



Pfaundler's reaction, 267 



Pfeiffer and Kolle's macroscopic agglu- 

 tination test, 288 



Pfeiffer' s bacteriolytic test, 342 

 experimental work, 862 

 in diagnosis of disease, 348 

 technic, 347 



Phagocytes, 144, 176 

 varieties, 177 



Phagocytic index, 200 



Phagocytosis, 145, 175 



experimental work, 829, 830 



history, 175 



in natural immunity, 168 



experimental work, 826 

 Metchnikoff's theory, 176 

 relation of body-fluids to, 184 

 of cell types to infection, 178 

 results of, 182 

 revised theory of, 186 

 spontaneous, 187 

 theory of immunity, 144 



and side-chain theory, compatibil- 

 ity, 155 



Phenomenon, Arthus, of anaphylaxis, 533 



