CHAPTER XXXI 

 SERUM THERAPY (Continued) 



NORMAL SERUM THERAPY 



THE field of serum therapy has been extended in recent years by the 

 successful use of normal serum in the treatment of various pathologic 

 conditions, particularly the hemorrhagic diseases, some toxicoses of preg- 

 nancy, and certain skin affections. 



NORMAL SERUM m THE TREATMENT OF HEMORRHAGE 

 Numerous reports by Welch, 1 John, 2 Franz, 3 Nohlia, 4 Reichard, 5 

 Perkins, 6 Claybrook, 7 and others have shown that injections of normal 

 human, horse, or rabbit serum are of considerable value in the treat- 

 ment of melena neonatorum, hemophilia, purpura hcemorrhagica, hem- 

 orrhagic retinitis, intestinal bleeding in typhoid fever and in connection 

 with cirrhosis of the liver, pulmonary tuberculosis, in some cases of uterine 

 hemorrhage, and in surgical operations upon icteric persons. Barringer 8 

 has reported the successful treatment, by. injections of fresh normal 

 human serum, of unilateral kidney hemorrhage in a hemophiliac, and 

 advises that this simple treatment should be tried in similar cases of 

 varicose veins of the renal papilla. Levison 9 has reported the successful 

 checking of hemorrhage from the urinary bladder following a simple op- 

 eration by performing cystostomy, removing clots, and filling the bladder 

 with sterile horse serum. 



This form of treatment is so simple and has been so successful in check- 

 ing hemorrhage in melena neonatorum and in other hemophilias following 

 injuries or operations that it should never be omitted. 



Defibrinated human blood, human serum, or the serum of the horse 



1 Amer. Jour. Obst. and Dis. of Women, etc., 1912, Ixv, No. 412. 



2 Munch, med. Wochenschr., 1912, lix, No. 4. 



3 Munch, med. Wochenschr., 1913, lix, 2905. 



4 La Presse M6dicale, 1913, xxi, No. 20. 



6 Jour. Amer. Med. Assoc. 1912, lix, 1539. 



6 Jour. Amer. Med. Assoc. 



7 Jour. Amer. Med. Assoc. 



8 Jour. Amer. Med. Assoc. 



9 Jour. Amer. Med. Assoc. 



1912, lix, 1539. 

 1912, lix, 1540. 



1912, lix, 1538. 



1913, Ix, 721. 

 829 



