862 



CHEMOTHERAPY 



The temperature of the solution at the time of injection should be 

 about that of the body. 



This flask is thoroughly shaken to insure an even diffusion of the 

 drug, and the contents poured into the cylinder from which it is admin- 

 istered, being filtered into this cylinder through a piece of sterile gauze 

 in order to remove any bits of broken glass from the ampule that may 

 have gained access or any other insoluble particles. (See Fig. 146.) 



FIG. 146. INTRAVENOUS INJECTION OF SALVARSAN. 



With this apparatus the operator may give an injection without assistance. 

 Notice the three-way cock, which permits the flow of salt solution or salvarsan solu- 

 tion at will. Usually a tourniquet composed of a simple rubber tubing and held in 

 position by a hemostat is better than the one shown, as the operator can quickly re- 

 lease it with least disturbance and loss of time. Note the funnels in both con- 

 tainers for straining the salvarsan solution and distilled water or salt solution. (After 

 the apparatus of Boehm.) 



Preparation of Dilute Neosalvarsan Solution for Intravenous Injec- 

 tion. This drug is readily soluble in water, forming a clear solution 

 which is ready for use. File the neck of the ampule, cleanse it with 

 alcohol, and break open. The contents are emptied directly into a flask 

 containing 100 to 150 c.c. of warm, sterile, freshly distilled water. On 

 gentle agitation the drug rapidly dissolves. Hot water should not be 

 used, nor should a solution be heated once it has been made. From 

 the mixing flasks the solution is poured into the cylinder through a 



