1 86 



BIOLOGY AND ITS MAKERS 



~K 



to make physiology broadly comparative. So comprehensive 

 was his grasp upon the: subject that he gained for himsel 

 the title of- the greatest physiologist of modern times, 

 brought together in his great work on the physiology of man 

 not only all that had been previously made known, carefully 

 sifted and digested, but a great mass of new information, 

 which was the result of his own investigations and of those 

 of -his students. So rigorous were his scientific standards 

 that* he did not admit into this treatise anything which ha( 

 been untested either by himself or by some of his assistant 

 or students. Verworn says of this monumental work, whic 

 appeared in 1833, under. the title Handbuck der Physiologie 

 des Menschen: "This work stands to-day unsurpassed in 

 the genuinely philosophical manner in which the material, 

 swollen to vast. proportions by innumerable special researchc 

 was for the first time sifted and elaborated into a unitai 

 picture of the mechanism within the living organism. In thi 

 respect the Handbuch is to-day not only unsurpassed, bi 

 unequalled." 



Muller was the most accurate of observers; indeed, he is 

 the most conspicuous example in the nineteenth century of a 

 man who accomplished, a prodigious amount of work all 

 which was of the highest quality. In physiology he stood 01 

 broader lines, than had ever been used before. He employed 

 even' means -at his- command — experimenting,, the observa- 

 tion of simple animals, the microscope, the discoveries 

 physics, in chemistry, and in psychology. 



He also introduced' into physiology the principles of psy- 

 chology, and .it is from the period of Johannes Muller "th* 

 we are to associate recognition of the close connection be- 

 ; tween the operations of the mind and the physiology of the 

 brain that has come to occupy such a conspicuous positior 

 at the present time. 



Muller died in 1858, having reached the age of fifty -seven, 



