304 



INFECTION AND IMMUNITY. 



Pancreotoxiii. 



It would appear that further observations are 

 desirable before conclusions can be drawn regard- 

 ing the value of nucleoproteid as antigen. 



sympathetic Brown Pusey has made the interesting sugges- 

 ophthaimia. tion in re g ar( j to sympathetic ophthalmia that the 

 disease may be due to the formation of autocyto- 

 toxins which are specific for the cells of the inner 

 surface of the ciliary body and iris. The disinte- 

 gration products of the corresponding cells in the 

 eye which was primarily injured would constitute 

 the stimulus to the formation of the specific anti- 

 bodies. The possibility is as yet a problematic 

 one. 



The experimental study of cytotoxic serums for 

 the pancreas has, up to the present time, thrown 

 little light on pancreatic diseases. It stated that 

 the serum may cause transient glycosuria, and it 

 is said to have an antitryptic action in experiments 

 performed in the test-glass. 



The results of different observers concerning the 

 action of antiserums for the adrenal gland are not 

 in entire accord. Although degenerative changes 

 may be caused in the gland when the serum is in- 

 jected, the action is not specific; the serum may 

 be highly hemolytic (Abbott). 



Ceni claims to have demonstrated in the circula- 

 tion of epileptics a cytotoxin which causes the ep- 

 ileptic attacks, and reports the production of a 

 specific antitoxin. 



Weichardt has published descriptions of a toxin 

 which is peculiar to states of exhaustion, giving 

 an account of the specific antitoxin which he pro- 

 duced by immunization. 



Other cytotoxins which have been prepared, as 

 those for the pituitary body, gastric mucosa and 



Other 



Toxin of 

 Exhaustion. 



