556 INFECTION AND IMMUNITY. 



pared from such animals as horses and rams. The 

 reports concerning the value of antigonococcus 

 serum have been as yet too varied to admit of a 

 conclusion. 



The subcutaneous injection of dead gonococci 

 for curative purposes has been apparently of little 

 value in acute urethral infections. In chronic 

 infections of the urethra, prostate and seminal vesi- 

 cles some satisfactory results have been obtained. 

 Cole and Meakins, and Irons find that the vaccine 

 treatment of gonorrheal arthritis is of value in 

 lessening the pain and in shortening the course of 

 the infection. 



VI. EPIDEMIC CEREBROSPINAL MENINGITIS. 



Microbes Acute inflammation of the meninges may be 



Causing _/. 



Meningitis, caused by a number of micro-organisms: Micro- 

 coccus meningitidis, also called the Diplococcus 

 intracellularis meningitidis, or briefly the men- 

 ingococcus; Diplococcus pneumonias; Streptococ- 

 cus pyogenes; Staphylococcus pyogenes; Bacillus 

 influenza; Bacillus pneumonice; Bacillus typho- 

 sus; Bacillus coli communis; Bacillus mallei; Ba- 

 cillus pestis. The first two of this number, the 

 meningococcus and the pneumococcus, in addition 

 to causing sporadic cases, also produce more or 

 less extensive epidemics of so-called primary men- 

 ingitis. That the pneumococcus may also cause 

 meningitis secondary to pneumococcus infections 

 in other parts of the body has been mentioned. 

 Also the meningitis caused by the other pyogenic 

 cocci usually is secondary to some other suppura- 

 tive focus, often the middle ear; that caused by 

 the organisms of typhoid, glanders, plague and 



