572 INFECTION AND IMMUNITY. 



tion. In man three members of the group they 

 may be the same organism or variations of a type 

 are of interest from the standpoint of infection : 

 Bacillus of Friedlander, the bacillus of rhinoscle- 

 roma and the ozena bacillus. 



In 129 cases of acute inflammation of the lungs, 

 Weichselbaum found the bacillus of pneumonia 

 nine times, twice with streptococci and once with 

 the diplococcus of pneumonia. The organism 

 causes lobular pneumonia more frequently than 

 lobar. The homogeneous non-granular surface, 

 and the large amount of fluid of a viscid or mu- 

 cous consistence, are characteristic anatomic feat- 

 ures. The alveoli contain massive numbers of the 

 bacilli. The bacillus of Friedlander is found also 

 as the cause of pyelitis, cystitis, pyelonephritis, 

 serous or purulent pericarditis, pleuritis and 

 meningitis, which may be accompanied by brain 

 abscesses. Meningitis when produced by this or- 

 ganism usually or always is secondary to infection 

 in other parts of the body by the same organism 

 (middle ear and accessory sinuses of the nose). 



An organism of the Friedlander type is found 

 with few exceptions in the tissues in rhinoscle- 

 roma, and by many is considered as the cause of 

 the condition. A similar organism is found con- 

 stantly in the secretions and crusts in ozena. 



Antiserums of distinct power have not been ob- 

 tained for members of the group. Prolonged im- 

 munization with some strains yields an agglutinat- 

 ing serum of low value. The agglutination re- 

 action 'is of no value for identification of the dif- 

 ferent members of the group, nor for clinical 

 diagnosis. 



