a 



e 



Fio. 92. STACKS OF ACTIVITY OF THE PANCREAS UNDER THE ACTION OF SECRETIN, AND OF 



STIMULATION OF THE VAGUS NERVE. 



a, 6, c, Stained with iron hfomatoxylin. 

 a, From fasting dog. 

 6, After action of secretin (acid in duodenum). 



C2'8 c.c. of juice secreted in four hours and ten minutes. 



Comparatively slight disappearance of granules and little structural change. 



c, After vagus stimulation. 



1 c.c. of juice in the first fifty-three minutes ; 5'1 c.c. in the next hour and a half ; C'4 c.c. in the last 



forty -one minutes. 

 Great disappearance of granules. 



d> . /. ff, Stained with eosin-orange-toluidine blue by Dpminici's method. The parts stained with eosin are shown 

 black ; those stained orange (drops of secretion within the cells and ducts) are shaded obliquely. 



d, After vagus stimulation. Granules stain red with eosin, but the contents of most of the vacuoles in the 

 cells and the secretion in the large duct stain orange. 



e, Vagus stimulation. Some vacuoles stain red ; others orange. 

 /, Weak stimulation of vagus. 



1 c.c. of juice in one hour and ten minutes. 



Empty open vacuoles are seen, which communicate with intercellular spaces. 

 g, Action of secretin. 



The juice in the duct stains red with eosin, like the granules. There are no vacuoles which stain with 

 orange. 

 (Babkin, Rubaschkin, and Ssawitsch, 1909. Figs. 1, 3, 5, 16, 18, 21, and 22 in order.) 



347 



