270 THE BLOOD. 



p. m. solids, with only 39.5 p. m. protein, and HALLIBURTON found only 

 25.4 p. m. protein in frog's blood. The relation between globulin and 

 seralbumin is, as shown by the analyses of HAMMARSTEN, HALLIBUR- 

 TON, and RuBBRECHT, 1 very different for various animals, but may also 

 vary considerably in the same species of animal. In human blood- 

 serum HAMMARSTEN found more seralbumin than globulin, and the 

 relation of serglobulin to seralbumin was as 1:1.5. LEWINSKY found the 

 relationship in man greater than 1, indeed 1:1.39-2.13. In regard to the 

 quantity of the remaining organic constituents of the serum we refer 

 the reader to ABDERHALDEN'S complete analyses. 



In starvation it seems, as first found by BURCKHARDT and then sub- 

 stantiated by other investigators, that the quantity of globulins relative 

 to that of albumin in dogs and also in rats (ROBERTSON 2 ) , is increased. 

 According to ROBERTSON, in the horse, ox and rabbit the reverse exists, 

 namely, the amount of albumin relative to the globulin increases in 

 starvation. A change in the relation with a decrease in the albumin 

 and an increase in the globulin may also occur in animals which have 

 been made sick or in part immune by inoculation with pathogenic 

 micro-organisms (LANGSTEIN and MAYER 3 ) . The total protein content 

 is raised in nearly all cases. The amount of fibrinogen in the plasma 

 is especially increased by pneumococci, streptococci, and pus-staphy- 



loCOCCi (P. MtJLLER 4 ). 



The quantity of mineral bodies in the serum has been determined by 

 many investigators. The conclusion drawn from the analyses is that 

 there exists a rather close correspondence between human and animal 

 blood-serum, and it is therefore sufficient to here give the analysis of C. 

 SCHMIDT 5 of (1) human blood, and BUNGE and ABDERHALDEN'S analyses 

 (2) of serum of ox, bull, sheep, goat, pig, rabbit, dog, and cat. The results 

 correspond to 1000 parts by weight of the serum. 



i 2 



K 2 0.387-0.401 0.226-0.270 



Na 2 4.290-4.290 4.251-4.442 



Cl 3.565-3.659 3.627-4.170 



CaO. 0. 155-0 . 155 0. 119-0. 131 



MgO 0.101 0.040-0.046 



PA, (inorg.) 0.052-0.085 



1 Abderhalden, Zeitschr. f. physiol. Chem., 25; Hammarsten, Pflliger's Arch., 17; 

 Halliburton, Journ. of Physiol., 7; Rubbrecht, Travaux du laboratoire de 1'institut 

 de physiologie de Liege, 5, 1896. 



2 Burckhardt, Arch. f. exp. Path. u. Pharm., 16; Githens, Hofmeister's Beitrage, 

 5; see also Morawitz, ibid., 7, and Inagaki, Zeitschr. f. Biol., 49; Robertson, Journ. 

 of bioL Chem., 13. 



3 Hofmeister's Beitrage, 5. 



4 Ibid., 6. 



6 Cit. from Hoppe-Seyler, Physiol. Chem., 1881, p. 439. 



