366 CHYLE, LYMPH, TRANSUDATES AND EXUDATES. 



volatile fatty adds, such as formic acid, butyric acid and valeric acid. 

 There are also found urea, glucose (in diabetes), bile-pigments, and bile- 

 adds (in catarrhal icterus). 



As more specific but not constant constituents of the pus must be 

 mentioned the following: pyin, which seems to be a nucleoprotein pre- 

 cipitable by acetic acid, and also pyinic add and chlorrhodinic add, which 

 have been so little studied that they cannot be more fully treated here. 



In many cases a blue, more rarely a green, color, has been observed 

 in the pus. This depends on the presence of micro-organisms (Badllus 

 pyocyaneus). From such pus FORDOS and LticKE 1 have isolated a crys- 

 talline blue pigment, pyocyanin, and a yellow pigment, pyoxanthose, 

 which is produced from the first by oxidation. 



Appendix. 

 Lymphatic Glands, Spleen and Endocrinic Glands. 



The Lymphatic Glands. The cells of the lymphatic glands are 

 found to contain the protein substances generally occurring in cells 

 (Chapter V) . According to BANG 2 they also contain histone nucleates 

 (nucleohistone) , but in smaller amounts and of a different variety from 

 the better-studied nucleohistone from the thymus gland. Proteoses 

 occur as products of autolysis. By a lengthy autolysis of lymph glands 

 REH S found ammonia, tyrosine, leucine (somewhat scanty), thymme, 

 and uracil among the cleavage products. Besides the other ordinary 

 tissue constituents, such as collagen, reticulin, elastin, and nuclein, there 

 occur in the lymphatic glands also cholesterin, fat, glycogen, sarcolactic 

 add, purine bases, and leudne. In the inguinal glands of an old woman 

 OIDTMANN found 714.32 p. m. water, 284.5 p. m. organic and 1.16 p. m. 

 inorganic substances. In the cells of the mesenteric lymphatic glands 

 of oxen, BANG 4 found 804.1 p. m. water, 195.9 p. m. solids, 137.9 total 

 proteins, 6.9 p. m. histone nucleate, 10.6 p. m. nucleoprotein, 47.6 p. m. 

 bodies soluble in alcohol, and 10.5 p. m. mineral constituents. 



The Thymus. The cells of this gland are very rich in nuclein bodies 

 and relatively poor in the ordinary proteins, but their nature has not been 

 closely studied. The chief interest is attached to the nuclein substances. 

 KOSSEL and LILIENFELD first prepared from the watery extract of the 

 gland, by precipitating with acetic acid and then further purifying, a 



1 Fordos, Compt. Rend., 51 and 56; Liicke, Arch. f. klin. Chirurg., 3; Boland, Cen- 

 tralbl. f. Bakt. u. Parasit., I., 25. 



2 Studier over Nucleoproteider, Kristiania, 1902, and Hofmeister's Beitrage, 4. 



3 Hofmeister's Beitrage, 3. 

 Lc. 



