SUMMKIt hlAKIUKKAS OF INFANCY. 135 



it down from its aqueous solution, consequently we must 

 -ay that it is not u globulin. 



This leaves us with no other choice than to place it 

 among the albumins, but we must admit that it possesses 

 properties which do not belong to the known albumins. 



The proteid prepared from cultures of the germ a is, as 

 seen under the alcohol, very light, flocculent, and perfectly 

 white, but so soon as it is brought in contact with the air 

 it begins to blacken, and finally dries down on the porous 

 plate in black scales. 



It possesses the same general properties in regard to the 

 action of solvents and other reagents which were found to 

 be possessed by the proteid obtained from cultures of x. 



The proteid of A is peculiar, inasmuch as it is practically 

 insoluble in water. 



These three proteids are highly poisonous. When in- 

 jected under the skin of kittens or dogs they cause vomit- 

 ing and purging, and, when employed in sufficient quantity, 

 collapse and death. Post-mortem examination shows the 

 small intestine pale throughout and constricted in places. 

 The heart has been in variably, so far, found in diastole and 

 filled with blood. The following brief notes from the 

 record of experiments will illustrate the nature of the 

 symptoms and the post-mortem appearances. 



A small amount of proteid frem bacillus x, dissolved in 

 water, was injected under the skin on the back of a kitten 

 about eight weeks old. Within one- half hour the animal 

 began to vomit and purge, and death resulted within eigh- 

 teen hours. The small intestines were pale, contracted in 

 places, and contained a frothy mucus. The stomach was 

 distended with gas and contained yellowish mucus. The 

 liver was normal, the spleen and kidneys congested, and 

 the heart distended. 



Another kitten was treated with the proteid from bacil- 

 lus a, dissolved in water. The vomited and fecal matters 

 in this case were green. The animal died after fifteen 

 hours, and presented appearances practically identical with 

 those mentioned above. 



A third kitten was treated with some of the proteid of 



