232 BACTERIAL POISONS. 



For its synthetic preparation see Ber. 24, l:>(>5 (Isiil). 

 The hose does not seem to possess a toxic action. 



The HYDROCHLORIDE, C 6 H U NO 2 .HC1, forms colorless, 

 stellate crystals, which are permanent in the air, and arc 

 extremely soluble in water, even in absolute alcohol. 



The AUROCHLORIDB, ( 1 5 H n NO 2 .HCl.AuCl 3 *+ H 2 O, is 

 obtained on slow evaporation, as large, well-Conned, heau- 

 tif'nl dark-yellow crystals. They are probably monoclinic, 

 contain water of crystallization, and melt at below 100. 



The PJ,ATINOCHLORIDE gave on analysis results cor- 

 responding to the formula (C 7 H 18 NO 2 .HCl) 2 PtCl 4 . This 

 may possibly be due to the presence of some higher homo- 

 logues of the base C 5 H U NO 2 . It forms fine orange-yellow 

 crystals, which arc very difficultly soluble in alcohol, easily 

 so in hot water, from which, on cooling, it crystalli/es in 

 beautiful plates. 



CHOLJNE GROUP. The following four bases arc closely 

 related, and, indeed, starting from choline, the oldest and 

 best-known individual, the remaining bases can be readily 

 prepared from it. Moreover, they can all l>e prepared 

 synthetically according to methods that will be subsequently 

 indicated. As choline is the most prominent member, we 

 have thought best to class these substances together as con- 

 stituting the choline group. It is very probable that my- 

 datoxine and mytilotoxine, when their constitution becomes 

 known, will be found to be homologues of certain members 

 of this group. 



NEURINE, C 5 H 13 NO = C 2 H 3 .N(CH 3 ) V OII. This sub- 

 stance was obtained and named thus by LlEBREICH (1S<;.">), 

 who prepared it by boiling protagon lor twenty-four hours 

 with concentrated baryta. Previous to its discovery as a 

 decomposition-product of protagon from the brain it was 

 prepared synthetically by HOFMANN (1858) by treat in- 

 trimethylamine and ethyl cue bromide with potassium hy- 

 drate or silver oxide. BAEYER (18(56), by boiling an alco- 

 holic extract of the brain with baryta water, obtained on 

 separation by three' different methods, a base, or rather a 



