'II KM IS I li\ OF Til K 1'ToM A I N i 



alcohol. For further details in regard to thi< base see 

 page 2 ')"). 



TYI:<>IO\ K ..\ has U-en obtained in poisonous chet-se 

 ( YAI<.II AN. \\ AI.I.A" i., WOLFF), in jwisonous ice-cream 

 (\"AI P (.M\N. Now. S HI.AUKK, LADD), in poisonous 

 milk (YAn.iiAN, Now, Ni:\\r>\. WAI.I.M K, FIKTII. 

 S< HKAKKK), and in mam-puffs (SrAX'n>.\). The methods 

 of separating this poison and its (-flirt ujxni animals have 

 already been given with sufficient detail. Chemically, it is 

 very instahle. When warmed with water to about 90, it 

 deoOBHMMeB. Hydrant sulphide also dec-omjxtses it, there- 

 fore all attempts to i>olate it by precipitation with some 

 la>-, >ueh as mercury or lead, and then removing the Iwsc 

 with hydrogen sulphide, have failed. Its unstable char- 

 acter is illustrated by the tact that it may disappear 

 altogether within twenty-four hours from milk rich in the 

 11 which is allowed to stand iu au open beaker. 



With jK)tassinm hydrate it forms a euni|>ound which 

 agrees in crystalline form, chemic-al reactions, and the |>er 

 cent, of potassium which it contains, with the compound of 

 dia/ol>enxole and potassium hydrate. This sul>stance is l>e>t 

 obtained from milk containing tyrotoxicon as follows : The 

 filtered milk, which is acid in reaction, is neutrali/ed with 

 sodium carbonate, agitated with an equal volume of ether, 

 alloweil to stand in a stoppered glass cylinder for twenty- 

 four hours, the ether removed, and alloweil to evaporate 

 -jxintaneonsly from an OJHMI dish. The aqueous residue is 

 acidified with nitric acid, then treated with an equal volume 

 of a saturated solution of potassium hydrate, and the whole 

 concentrated on the water-bath (this compound is not 

 d -corniced below 130). On Ix-ing heated the mixture 

 MOOflMI yellowish-brown, and emits a peculiar aromatic 

 odor. ( >n cooling the tyrotoxk-on eom|x>und forms iu 

 beautiful, six-sided plates along with the prisms of potas- 

 sium nitrate. 



With equal parts of sulphuric and carbolic acids, pure 

 tyrotoxieon gives a green coloration, but in whey the color 

 varies from yellow to orange-red. This color reaction may 



