384 BIBLIOGRAPHY 



corresponds to the diminution of glycogen. On account of this 

 result, Seegen thinks that there is in the liver some other 

 polysaccharide besides glycogen. This polysaccharide contains 

 nitrogen. 1 These workers also found that when peptone was 

 added to a liver mush, reducing sugar was produced in increased 

 amount as well as substances from which sugar could be pro- 

 duced by hydrolysis. Of course peptone is not normally carried 

 as such to the liver, being converted, in its passage through the 

 intestinal epithelium, into native proteid. The result is never- 

 theless of interest, because it opens up a new line of research, 

 viz. to study the effect of adding the various decomposition pro- 

 ducts of proteid to active liver tissue. 



The following papers are referred to by numbers in the text. 

 In all of them detailed literary references will be found : 



1 Cl. Bernard, Lecons de Physiologie experimental appliquee a la 

 medecine, Paris : chez J. B. Bailliere (1855). 



2 Cl. Bernard, Lemons sur le Diabete et la Glycogenese animale, Paris : 

 Librairie J. B. Bailliere et Fils (1877). 



3 Leo Langstein, Die Bildung von Kohlehydraten aus Eiweiss. Ergebnisse 

 der Physiologic, l er Jahrgang : Bioch. Abtli. p. 69 (1902). 



4 Leo Langstein, Die Kohlehydratbildung aus Eiweiss. The same, 

 3 cr Jahrgang, I. Abth. p. 453 (1904). 



5 Orgler undNeuberg, Uber Chondroitiuschwefelsaiire und das Vorkommen 

 einer oxyaminsaiire in Knorpel. Ztschr. f. physiol. Chemie, Bd. 37, p. 407. 



E. F. W. Pfluyer, Glykogen. Arch. f. <i". ges. Physiologie, Bd. 96, S. 1 

 (1903). 



7 B. Schondorff, Uber den Maximalwerth des Gesammtglykogengehalt 

 von Hunden. Arch. f. d. ges. Physiologie, Bd. 99, S. 191. 



8 Bendix, Uber physiologische Zuckerbildung nach ErweissedaiTeiclumg. 

 Ztschr. f. phys. Chemie, Bd. 32, p. 479 (1901). 



9 /. Frentxel, Uber Glykogenbildung im Tierkorper nach Fiitterung mit 

 Holzzucker. Arch. f. d. ges. Physiologie, Bd. 56, p. 273 (1894). 



10 F. W. Pavy, The Physiology of the Carbohydrates, London (1893). 



11 Schondorff, Die Entstehung von Glykogen aus Eiweiss. Arch. f. d. ges. 

 Physiologie, Bd. 88, p. 339 (1902). 



12 Blumentlial und Wohlgenwth, Uber Glykogenbildung nach Eiweiss- 

 futterung. Berlin Klin. Wochenschr., Bd. 38, p. 391 (1901). 



1 This polysaccharide can be isolated from a decoction of liver by first of all 

 precipitating all the proteid and glycogen with tannic acid, then removing the 

 excess of tannic acid, evaporating in vacuo and adding alcohol to the residue. 

 The resulting precipitate is largely soluble in water and yields on hydrolysis 

 with acid from 50 to 70 per cent, of sugar. It contains G to 7 per cent, of 

 nitrogen. 



