APPENDIX A. 



The following cuts are copied from some of the twenty- 

 eight photomicrographs exhibited at the lectures. It has 

 been deemed advisable to print them here with the brief- 

 est possible summary of the remarks which accompanied 

 their exhibition. 



In erysipelas the lymph-spaces just at and in front of 

 the advancing edge of the inflamed area contain micro- 

 cocci. These organisms have been isolated by cultiva- 

 tion on solid media (Koch's method) by Fehleisen. He 

 reports the successful induction of erysipelas by inocu- 

 lation with the micrococci thus isolated, in eight rabbits 

 and in one human patient. 



Recurrent or relapsing fever is characterized by the 

 presence of Obermeier's spirillum in the blood. 



As yet no successful inoculation with the isolated spi- 

 rilla has been reported. 



A short, thick bacillus is found post-mortem in the 

 liver, kidney, spleen, and lymph-glands in the majority 

 of cases of typhoid fever (Eberth, Koch, Friedlander) ; 

 and larger bacilli in the vicinity of the intestinal ulcers 

 (Klebs). Maragliano asserts the presence of both vari- 

 eties in blood drawn by a hypodermic syringe from the 

 spleen in fifteen cases (intra vitam). It would seem, 

 however, that he protests too much ; for even post-mor- 

 tem only Eberth' s, never Klebs' bacilli, are found in the 

 spleen. 



In croupous pneumonia small bacteria have been 

 found at the edge of the advancing inflammation (like 

 the micrococci in erysipelas ) ; also in some internal or- 

 gans. The same bacteria have been found in the lung 

 immediately post-mortem, and even intra vitam. 



Endocarditis ulcerosa seems to be one of the forms of 

 pyaemia, sometimes of spontaneous (i.e., undiscovered) 

 origin. 



