78 ON DIGITALIS, WITH SOME . 



the urine and urinary constituents, with a view of determininpf, 

 if possible, the changes effected in tissue changes under the use 

 of digitalis, I have thought it not out of place to note down the 

 chief facts which I have personally observed, and, in doing this, 

 I will adhere strictly to the order adopted by Mr. Parkes in his 

 excellent work on the Urine. 



Amount of Constituents. 



In the change of French into English weight, I have reckoned 

 the gramme as equal to 1 5 '43 grains, and the English fluid oz. 

 as equal to 284 cubic centimetres. 



On an average of 150 observations, chiefly taken during 

 winter, but a few during summer, I find the amount of 

 urine . . 1124 cub. cent, or 39-J ounces. 



The maximum amount was 1855 c.c. or 63J „ 

 The minimum „ „ 610 „ or 21 J „ 



This difference is, however, much more than my normal, the 

 one being in summer and the other in winter ; and, moreover, 

 the large number occurred after I had been taking digitalis. 



My mean variation, from the lowest to the highest, is about 

 487 C.C. or 13f oz. 



This variation amounts to more than a third of the total 

 amount, and this is therefore considerably above the average, 

 which is i. 



Urea. — The mean amount of 105 analyses of urea is — 



3 3 '44 grams, or 516 grains per day, 



1-39 „ 21 J „ per hour. 



The mean variation is 9*36 „ 144^ „ or rather 



more than I, while the average amount is |th. 



PliospTioric Acid. — From 108 analyses I find the average 

 amount of PO5, to be 31 grams, or 47^ grains daily, 



2 „ hourly. 

 The mean variation is 0-96 „ 14i „ „ 



which is less than usual, the mean being 35 to 50 per cent. 



Chlorine. — From 80 analyses I find the average amount to be 



