128 ox DIGITALIS, WITH SOME OBSERVATIONS ON THE URINE. 



At 2.55' Much the same — grumbling. 



3. I now had to go to a class, and did not see the dog again till I 



returned at 5.30'. The dog was then stiff and cold. The 

 tongue was protruded at the side of the mouth; the jaws shut; 

 saliva on the chops ; some prostatic mucus at the orifice of tlie 

 urethra (not examined microscopicallj). Post-mortem — Lungs 

 were of a light pink colour, much collapsed. Vena cava and 

 venous system gencrallj^ full of black blood, and very turgid. 

 Right auricle and ventricle distended with black blood, which 

 was somewliat curdled — not in firm clots. Left side of heart 

 natural in colour; contained a little blood, also somewhat 

 curdled. Liver congested. Gall-bladder distended. Bladder 

 firmly contracted, and empty. 



Exp. XIII. — Jan. 16. — A small English terrier, very thin, was taken for 

 experiment. 



2.29' P.M. — The dog was shivering; the heart sounds normal in character, but 

 altered in rhythm, being very slow between the rigors, but during their continu- 

 ance the beats were very rapid. The shiverings lasting each for about 4 seconds,, 

 and the interval about 1 minute. There was no murmur with the cardiac 

 sounds. In the back room in which the dog had been kept, there was a bag of 

 digitalis leaves on which it had lain, and a good many were scattered on the floor, 

 so that the dog may have taken some along with its food before, and this possibly 

 may have been the cause of the curious rhythm of the heart, and of the- 

 shiverings. 



2.30' P.M, — I injected \ a grain of digitaline suspended in rather less than 

 1 oz. of water into the cellular tissue at the side of the lumbar vertebra. 



2.37' 15, — The dog suddenly started up, and ran to the end of his tether. 



2.37' 40.— Sat down on haunches, 2.38' 30.— Rose again. 2.39'.— Straddles 

 and whimpers, and jumps about. In attitude of attention ; then runs about^ 

 and again stands, apparently listening intently, 



4.40' 20. — Whines and licks the place where the injection was made. On 

 being loosed he shook himself, ran off, and sat down. Was restless, and seemed 

 thirsty, so I gave him some water, 



2.50', — Heart sounds as before. 3.30', — As before ; no murmur. 



3.50'. — Vomiting, 4, — Purging. 4.10', — Vomiting. 4.20'. — Again vomiting,, 

 and again at 5.30'. I then left for the night. 



On the following day (the 17th) the dog lay curled up on the floor for the 

 greatest part of the day, but could stand or walk. At 5.35' p.m. the dog had 

 refused food, so to kill it at once I poured into its mouth some alcoholic solution 

 of extract of digitalis, most of which it swallowed. 5.37'. — The dog vomited 

 some white mucus, then lay quite quiet. 5*40', — Again vomiting, 5.44', — 

 Seems livelier, 5,45', — Again vomiting. 5.46', — Purging. 



On the 18th, at 10 a.m., the dog was lying curled up ; it rose once or twice, 

 but with some difliculty, and straddled very much when standing. Grait totter- 

 ing and unsteady. 10.30', — Struggles in vain to rise. Progresses along the 

 floor, partly on its side and partly on its belly. Ineffectual efforts to rise. 

 Heart's action very weak, but seems more regular. Surface cold. Respirations 

 7i per minute. Pupils contracted. The dog lay so, occasionally making slight 

 Tain efforts to rise for about an hour more, and then till 3,20' p.m, it lay as if 



