EFFFXT OF A MODERATE DOSE ON MAMMALS. 485 



Experiment III. — April 28. 



Seven c.c. of a similar solution to that used in Experiments I. 

 and II. were injected beneath the skin ot* a moderate-sized, 

 well-nourished cat. In 15 minutes the animal vomited for the 

 first time, and this vomiting was repeated four times within the 

 next hour and twenty minutes. During tlie rest of the day it 

 remained quiet, without further vomiting, and with no paralysis 

 or disturbance of muscular movements. It appeared to be quite 

 comfortable. 



On the following day it remained sitting in one position, and 

 refused its food and milk. There was no vomiting, and no 

 urination or defalcation. When disturbed, it would immediately 

 return to its former position in a mechanical manner. 



On the following day it passed a very small quantity of 

 fa?ces ; it was not observed to urinate, and, as before, it neither 

 ate nor drank anything. It vomited once, very slightly. 



From this time forwards, for a fortnight after the administra- 

 tion of the poison, the cat remained in this condition, neither 

 eating nor drinking, although tempted to do so with milk and 

 meat; and even when a live mouse was placed before it, it 

 merely pricked up its ears, and looked eagerly at it, but did not 

 touch it, nor did it pass urine or feces once for the last eleven 

 days. 



It sat always in one position unless disturbed, and though it 

 got steadily weaker, did not lose flesh in the way an animal 

 starved would have done. The temperature on May 2nd was 

 ^8" C. 



Five days after the poison was given a subcutaneous abscess 

 formed over the right scapula and ribs. ]^o other lesions were 

 ascertained during life. The abscess did not form at the seat of 

 puncture. 



It died, apparently from exhaustion, fourteen days after the 

 poison was administered. 



Post- m ortem Examination. 



Eigor mortis well marked. 



*5ubcutaneous tissue contained a fair amount of fat. 



