626 SCIENTIFIC AND APPLIED PHARMACOGNOSY 



cording to Schmiedeberg and Kiliani, it is a mixture of several sub- 

 stances. 



Digitalin Schmiedeberg is a chemically uniform, amorphous 

 body of the formula (CsHgCb)?. 



Digitalinum fluidum was the name given by Engelhardt to a 

 liquid, volatile, oily substance obtained from digitalis leaves, and 

 which he regarded as the active component of digitalis. 



Digitalinum Pharmacopee frangaise, 1908, is identical with 

 digitoxine Pharm. franc,. 



Digitalinum Gallicum amorph. is obtained from digitalis leaves 

 according to the method given in the Pharmacopee frangaise, 1884. 

 It also bears the name of " digitaline chloroformique." It is com- 

 pletely soluble in chloroform and practically insoluble in water. 



Digitalinum Gallicum crystallisatum is either digitalin Nativelle 

 or digitoxine Pharm. frang. 1908. 



Digitalinum Germanicum is an amorphous product obtained 

 from digitalis seeds, and is soluble in water. It consists principally 

 of digitalinum verum, digitalein and digitonin. 



Digitonin resembles in its physiological action quillajasaponin, 

 and on hydrolysis yields dextrose, galactose and digitogenin. It is 

 crystalline, soluble in water, somewhat soluble in alcohol, and 

 remains colorless on treatment with hydrochloric acid; but a dilute 

 sulphuric acid solution becomes garnet-red in color on boiling for 

 some time. 



Digitonin, when anhydrous, occurs as an amorphous body, while 

 with SEbO it is a crystalline, chemically uniform body. 



Digitonin, amorphous, is digitonin Schmiedeberg. 



Digitonin cryst, is digitonin Kiliani. 



Digitonin Kiliani is pure, crystalline, hydrated digitonin 



Digitonin Schmiedeberg is amorphous, anhydrous, digitonin. 

 According to Kraft, digitonin Schmiedeberg and digitonin Kiliani 

 are not identical; he therefore suggests the designation " digit- 

 saponin " for digitonin Schmiedeberg. 



Digitalein Nativelle was described by Nativelle as a physiolog- 

 ically active glucoside, soluble in water and obtained from digitalis 

 leaves. 



Digitalein Schmiedeberg is a glucoside soluble in water. Kiliani 

 at first doubted the chemical individuality of the digitalein of Schmie- 

 deberg. Keller and Hondas also took it to be digitonin. But 

 Kiliani proved later that the seeds and leaves of digitalis contain a 

 cardiac poison, soluble in water, which contains no digitalin, the 



