LE CT URE XI. 



MARCH 27, 1858. 

 PIGMENTARY ELEMENTS IN THE BLOOD. NERVES. 



Melansemia Its relation to melanotic tumours and colorations of the spleen. 



Red blood-corpuscles Origin Melanic forms Chlorosis Paralysis of the respira- 

 tory substance Toxicsemia. 



The nervous system Its pretended unity. 



Nerve-fibres Peripheral nerves : their fasciculi, primitive fibres, and perineurium 

 Axis-cylinder (electrical substance) Medullary substance (Myeline) Non- 

 medullated and medullated fibres Transition from the one kind to the other : 

 hypertrophy of the optic nerve Different breadth of the fibres Their termina- 

 tions Pacinian and tactile bodies. 



GENTLEMEN, I have still some observations to make 

 to you in reference to the changes of the blood, more for 

 the sake of completeness than because I am able to offer 

 to you in doing so any decisive points of view. 



In the first place I wish to mention one other condi- 

 tion which has recently been a great deal talked about, 

 and might, when occasion offered, present increased in- 

 terest to you, the so-called melanamia. This is a condi- 

 tion most nearly connected with leukaemia, inasmuch we 

 have in it to deal with elements, which, like the colour- 

 less corpuscles in leukaemia, make their way from defi- 

 nite organs into the blood and circulate with it. The 

 number of recorded observations concerning this matter 

 is already tolerably large, indeed I might almost say, 



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