LECTURE XIX. 



APRIL 24, 1858. 



PATHOLOGICAL, AND ESPECIALLY HETEROLOGOUS NEW- 

 FORMATION. 



Consideration of some forms of pathological formation of boue. Soft osteoma ol 

 the maxillee Rickets Formation of callus after fracture. 



Theory of substitutive new-formation in opposition to exudative Destructive 

 nature of new-formations Homology and heterology (malignity) Ulcera- 

 tion Mollities ossium Proliferation and luxuriation Medulla of bones, and 

 pus. 



Suppuration Its two forms: superficial, occurring in epithelium; and deep, in con- 

 nective tissue Eroding suppuration (skin, mucous membrane) : pus and mucus- 

 corpuscles in their relations to epithelium Ulcerative suppuration Solvent 

 properties of pus. 



Connection of destruction with pathological growth and proliferation Correspon- 

 dence of the first stage in pus, cancer, sarcoma, etc. Possible duration of the 

 life of pathologically new-formed elements, and of pathological new-formations 

 considered as wholes (tumours) Compound nature of the larger tuberous* tu- 

 mours (Geschwulstknoten), and miliary character of the real foci (Heerde) 

 Conditions of growth and recurrence : contagiousness of new-formations and 

 importance of the anastomoses of cells Cellular pathology in opposition to 

 the humoral and neuristic General infection of the body Parasitism and 

 autonomy of new-formations. 



GENTLEMEN, I will to-day begin by laying some 

 pathological preparations before you, for which I re- 

 mained in your debt last time. 



I begin with an interesting object which has lately 

 come into my hands, and exhibits with a distinctness 



* Tuberous, in contradistinction to infiltrated, tumours (infiltrations). From a 

 MS. Note by the Author. 



4T1 



