480 LECTURE XIX. 



pletely with calcareous salts. In other places on the con- 

 trary the fusion of the capsules with the intercellular 

 substance takes place very rapidly ; the new intercellular 

 substance formed by this fusion assumes a coarsely fibrous 

 appearance, and in the place of several groups of carti- 

 lage-cells we see a fibrous mass, containing jagged osse- 

 ous (bone-), or osteoid corpuscles. There is therefore no 

 sharply defined boundary in the tissue, but the condensed 

 or fibrous substance, which surrounds the jagged bodies, 

 is directly continuous with the translucent substance 

 which holds the cartilage together. Essentially, however, 

 it is the same structure.* 



This isolated transformation of single cartilage -cells 

 into bone corpuscles is obviously of the greatest impor- 



Fio. 134. 



JKM8TMKS 

 CO I 



Fig. 134. Insular ossification in ricketty diaphysal cartilage, c, c. Ordinary 

 growing (proliferating) cartilage, c', increasing thickening of the capsules with for- 

 mation of an indented cavity (osteoid cartilage-cells), eo', calcification of similar, 

 still isolated cartilage cells, co, commencing fusion of the capsules of calcified carti- 

 lage-cells, o, osseous substance. 300 diameters. (Of. Archiv. f. path. Anat , Vol. 

 XIV., Plate I. 



* The following section, including the history of the formation of callus, has been 

 transferred to this place from the next lecture, inasmuch as a better understanding 

 of it is thus insured. 



