GUAM AGRICULTUEAL EXPERIMENT STATION. 29 



The body temperature during an attack of fever will vary between 

 104° and 109° F. The animal shows great depression, dullness, 

 pain, and stupor, and is often noticed resting nose in tie chain in a 

 peculiar manner. A slight edema occurs in the submaxillary region, 

 A rough, scaly, and mangy appearance of neck and shoulders is 

 sometimes present, a condition furnishing an excellent hiding place 

 for ticks. The body becomes emaciated and debilitated. The appe- 

 tite is impaired but seldom wholly lost. The mucous membranes of 

 the eyes and of the mouth are pale and anemic. Rumination is 

 irregular. In acute attacks, the eyes are bright and feverish, though 

 later they may appear dull and sunken, a profuse watery discharge 

 affecting them. Salivation is sometimes present. Feces in the first 

 stages are glazed and often streaked with blood, and in later stages 

 a severe diarrhea is present, the feces being watery, black, and very 

 foul smelling. The superficial l,ymph glands are noticeably enlarged. 

 The pulse varies between 70 and 110 beats per minute, and in severe 

 cases a jugular pulse is always present. Breathing is labored, with 

 respirations between 25 and 35 per minute. Abnormal murmurs are 

 often present. The gait is weak and uncertain, noticeably so in the 

 liind quarters. In walking, each hind foot is carried to the opposite 

 side before it is placed on the ground, the feet often interfering w^ith 

 each other and causing stumbling. In some cases the feet are ex- 

 tremely tender, and the animal frequentl}^ shifts the weight from 

 one foot to the other. The mere weight of a hand over the loins will 

 cause a sinkino- of the back. The extremely weakened condition of 

 the hind quarters often makes it difficult for the animal to regain a 

 standing position. The condition of the urine known as hemo- 

 globinuria has not been present in any case. 



A post-mortem examination of an animal dying of the chronic 

 form of the disease disclosed the following lesions : Body emaciated ; 

 mucous membranes anemic; blood pale and w^atery; lymph glands 

 swollen and hemorrhagic; liquid effusions in the pleural cavity; 

 mucous membranes of the large intestines congested with necrotic 

 areas; spleen slightly enlarged, softened, and somewhat engorged; 

 liver enlarged, yellowish, mottled, and showing fatty degenerative 

 changes; gall bladder distended and filled with a semifluid con- 

 taining yellow flakes and mucus; bile ducts greatly distended and 

 filled with a hard, flaky substance ; heart pale and showing degener- 

 ative changes; kidneys slightly congested; and urine practically 

 normal. Although no flukes were present in this case, the condition 

 of the liver, together with the contents of the bile ducts, was similar 

 to those found commonly in the fluke-infested livers of native 

 animals. 



In considering the eradication of the tick in Guam it is well first 

 to fully appreciate the conditions as they exist here. The surface of 



