Cellular Content of Milk. 



27 



such cells may be found even in the epithelial groups, which is an 

 additional proof that they with certainty represent epithelial cells. 



The cells are from 5 to 25, even to 47 p> in size (Schulz). Not 

 infrequently 2 to 3 nuclei of oval or roundish shape are present. 

 The author has never observed more than one nucleus, and be- 

 lieves, with Popper and Schulz, that the appearance of more than 

 one nucleus results from two cells lying on each other, in which 

 case the cell thus formed may appear to possess two or more nuclei. 

 Migrated macrophages may also simulate a polynuclear 

 appearance. 



Notinfrequentlyepi- Fig 12< 



thelial cells are thrown ' 



off, with a single large 

 fat globule in the body 

 of the cell, known as 

 " seal-ring cells." In 

 such cases the fat glob- 

 ules have a "moon" or 

 "cap" appearance. 



4. Leucocytes of all 

 forms are frequently met 

 with in milk such as 

 mononuclear basophiles, 

 eosinophiles, polynuclear 

 basophiles, acidophiles, 

 or cells with neutrophilic 

 and eosinophilic granules 

 in the protoplasm. 



If the polynuclear 

 cells show no nuclear 

 bridges, they may be 

 found with % or more 

 spherical shaped nuclear 

 granules (spherical gran- 

 ule polynuclear leuco- 

 cytes, Babs.) The nu- 

 cleus is usually in the 

 shape of a ribbon, or clover leaf, or heartshaped. The protoplasm 

 usually contains fat globules, which in stained preparations appear 

 as fine vacuoles. 



The lymphocytes are small cells with round nuclei and a very 

 small border of protoplasm. According to Schulz they never con- 

 tain fat. Large mononuclear leucocytes are also supposed to be 

 present in the milk. If they gorge themselves with fat they are 

 filled to their fullest extent, and can no longer be distinguished 

 from fat-containing epithelial cells. 



5. The red blood cells may be seen as small, round or thorn- 



Sediment in milk of a cow after milk stasis. Numer- 

 ous desquamated epithelia, among these an "albu- 

 minophore," and polynuclear leucocytes. 



