28 



Microscopy of Milk in General. 



apple shaped bodies, with metachromatic staining substances. 

 They may be readily recognized as erythrocytes. 



6. Degeneration of these various kinds of cells may result in 

 the finding of the most peculiar formations. 



The protoplasm of the epithelial cells becomes shredded ; the 

 nucleus splits up and eliminates its chromatin into the plasma in 

 the form of dust or flakes. It diffusely passes into the cell pro- 

 toplasm, which appears darkly stained, and in the place of the 



Fig. 13. 



The formation of large colostral spheres and desquamation of "seal-ring cells." 



1 X 800. 



nucleus a pale vacuole appears. If the breaking down continues 

 there may appear a disintegration of the cell and of its nucleus into 

 small droplets and fragments of roundish appearance, either with 

 or without a lightly stained border around a small darkly stained 

 center of chromatin (Heidenheim, Cohn, Popper, Schulz). These 

 chromatin flakes are probably identical with the so-called free 

 nuclei (Michaelis), which were also observed by Lenfers. 



The flakes which result from chromatolysis have been des- 



