Milk Concrements. 



31 



radiated stripes appear upon its surface in consequence (Fig. 13, 

 Fig. 16 and Table L). 



While the alveolar epithelium succumbs to the pressure of the growing concrement, 

 and may be absorbed for some time, the concrement resists the influences of the organs, 

 and finally is surrounded by connective tissue. Zimmermann states that the bodies may 

 be either in the alveolus or on or under the epithelial layer, and even free in the con- 

 nective tissue. These observations have been confirmed by the author. 



They stain with methylene blue, iodine green, and gentian 

 violet, similar to other amyloid substances, but do not give the 

 starch reaction with 



iodine solution and sul- Fig. 16. 



phuric acid (Zimmer- 

 mann, and author's ob- 

 servations). Wederhake 

 and Winkler claim to 

 have obtained a bluish 

 violet coloration with 

 iodine. 



The corpora amy- 

 lacea of the mammary 

 glands resist few acids 

 (sulphuric acid, hydro- 

 chloric acid). Otto- 

 lenghi and Zimmermann 

 obtained a solution with 

 pure sulphuric acid. 



They are therefore 

 pure concrements of se- 

 cretion which form un- 

 der peculiar conditions. 

 Their quality varies, 

 depending on the char- 

 acter of the precipita- 

 tions, which combine to 



lOrm them. Lime concrement in the milk sediment of a cow. 



1 X 1000. 



What remarkable significance may be attached to such conditions may be indicated 

 by the views of Herz, who considers them as the initial formation of casein, and those 

 by Winkler, who believes that they change into fat or that they are degenerated 

 epithelium. 



Leucocytes also crowd upon these bodies, and attempt to dis- 

 solve them just as osteoclasts attack bones. Under their influence, 

 combined with that of the body juices, a destruction, solution and 

 absorption of the concrements may take place, or on the other hand 

 new layers of thickened secretion may form around the old debris, 

 and a new concrement develops. 



This describes, with the exception of the fat globules, the cell 

 elements which may be demonstrated under the microscope, as far 

 as they originate from the udder of the cow. The fat globules will 

 be discussed under the heading of milk fat. 



