78 Effect of Internal Influences. 



changes of the secretion appear slowly, and relatively late, while 

 inflammations of an acute character very quickly produce a tre- 

 mendous change in the secretion, the mixing of which with market 

 milk would be the grossest negligence. It is to be regretted that 

 such cases occur. 



Appearance of affected milk : In forms of inflammation which 

 are associated with rapid development, painful swelling and in- 

 creased temperature of the udder, the milk usually has a bloody 

 discoloration, later becoming yellow (colostrum-like), and finally 

 changes into a custard, or honey-like secretion, in which thick, 

 yellow and yellowish-brown flakes are suspended in a more or less 

 clear serum or plasma. 



Such changes are observed in samples of milk in acute forms 

 of mastitis, through infection of bacteria of the colon group, in 

 mixed infections, in acute attacks or in great extension of strep- 

 tococcic mastitis, and in infections with the Bacillus pyogenes, etc. 



In chronic affections the milk changes only slightly or not at 

 all during the beginning of the disease, or it may appear normal 

 long before the disease as such is considered cured. If such nor- 

 mal appearing milk from affected quarters is allowed to stand 

 for several hours a white, yellowish-white or yellowish sediment 

 settles to the bottom. At the same time the quantity of cream is 

 increased and changed, appearing yellowish, tenacious, and when 

 shaken it assumes a cloudy or wavy appearance. If the migration 

 of the pus corpuscles from the blood vessels becomes more inten- 

 sive the milk appears thick, yellowish, cream-like, and after stand- 

 ing separates into a yellowish-white to ocher colored sediment, 

 which may amount to two-thirds or more of the entire mass, and 

 into a dark, transparent, yellowish-grey to greenish-yellow skim 

 milk. The sediment layer is at times increased, at other times 

 decreased. The cream becomes granular, shredded, and tenacious. 

 If red blood corpuscles are eliminated in great numbers they col- 

 lect in the form of a red disc on the yellow to yellowish-brown base, 

 which is composed of leucocytes and coagulation masses. In 

 hemorrhagic stages of the inflammation the milk is pinkish or 

 brownish-red; by sedimentation it separates into a Bordeaux-red 

 or rust-colored precipitate, and a pinkish-red layer of cream over 

 the reddish-gray skim milk. 



In other cases the milk becomes grayish and watery, and only 

 a few thin conglomerates and fat globules indicate the layer of 

 cream. 



Cream and sediment are especially rich in cells in all forms 

 of inflammation. Epithelial cells are desquamated into such milk 

 in the form of colostral cells, or entire epithelial bands, and numer- 

 ous polynuclear leucocytes, besides single epithelial cells, into 

 which macrocytes penetrate (albuminophores), erythrocytes, cell 

 debris, fragments of nuclei, as well as Nissen's globules are found. 



Besides concrements of the most varied quality, casein and 



