THE CLASSIFICATION OF BACTERIA 355 



Glucose bouillon. Acid ; no gas. H..S slight. Indol positive. 



Pattwgenesis. Subcutaneous inoculations of guinea pigs cause death in 36-72 

 hours. There is oedema, hemorrhage, and a fibro-purulent exudation 

 about the point of inoculation, hemorrhagic enlargement of lymph 

 glands, congestion of the lungs and other organs, hemorrhage of supra- 

 renal capsules. There is generally only a local development of bacteria. 



Habitat. Associated with diphtheria and present in the throats of persons who 

 have been exposed to infection. 



10. Mocobact. pseudodiphthericum (Kruse) 



Pseudodiphtheria Bacillus Loffler: Centralblatt f. Bakteriol., II, 1887, 105. 

 Xerose Bacillus Neisser-Kuschbert : Centralblatt f. Bakteriol., I, 178. 

 B. pseudodiphthericus Kruse: Fliigge, Die Mikroorganismen, 1896. 



This may be only a non-virulent variety of the preceding. In the more 

 marked types it may be distinguished from the preceding by being 

 shorter and thicker. On glycerin agar and in bouillon it grows rather 

 more abundantly. According to Escherich and others, the pseudo- 

 diphtheria bacillus during the first 2-3 days of growth causes an increased 

 alkalinity of the medium (bouillon), while the true diphtheria bacillus 

 causes a diminished alkalinity. 



Habitat. Isolated by Hoffmann, etc., from the healthy mouth and throat ; by 

 Neisser-Kuschbert, etc., in xerosis and other affections of the conjunctiva. 



11. Mycobact. pseudotuberculosis (Kutscher) 



B. pseudotuberculosis-murium Kutscher: Zeitsch. f. Hygiene, XVIII, 1894. 

 B.pseudotuberculosis-ovis Preisz: Annales Pasteur Inst. 1895. 



Morphology. Bacilli like those of diphtheria. Stain by Gram's method. 



Gelatin colonies. Granular, with erose borders. 



Potato. No growth. 



Milk. Unchanged. 



Bouillon. Slight growth. 



Pathogenesis. Subcutaneous inoculation of mice result in abscesses at the 

 point of injection, with a general inflection and death in 5-8 days. Intra- 

 peritoneal and intrapulmonary injections cause death, with pseudotuber- 

 cular lesions. Subcutaneous and intraperitoneal inoculations of guinea 

 pigs cause pseudotuberculosis of the abdominal viscera, and death in 

 2-10-35 days. 



Habitat. Found by Kutscher in cheesy nodules in lung and pleura of a 

 mouse ; by Preisz and Guinard in pseudotuberculosis of sheep ; and by 

 Kitt from a cheesy pneumonia of cattle. 



