CHAPTER VIII 



ALTERATIONS IN STATE OF THE ALKALI 

 PROTEINS WITH LAPSE OF TIME 



MORE detailed experiments have soon shown that the physico- 

 chemical properties of alkali protein solutions alter with lapse 

 of time in a remarkable manner. This occurs even at room 

 temperature and on addition of quite low concentrations of 

 alkali when no question of breaking down of the protein can 

 arise. The compounds of acids and proteins, on the other hand, 

 are remarkably stable under the same conditions. These 

 changes of state with time were first investigated in a detailed 

 manner by C. Schorr * at this Institute. He found that the 

 viscosity of an approximately i per cent, serum albumin in 

 alkali concentrations of 0-04 N upwards rose with time to a 

 maximum value and then decreased again. The following table 

 gives typical results for the viscosity at 24-5. 



Table 58. 



* Biochem. Zeitsch., 1911, 37, 424. 



