15 



garded as proof of the etiological connection between a micro-organism 

 and disease at the time when Dr. Detmers made his observations are 

 no longer considered sufficient. I believe that Dr. Detmers would 

 readily acknowledge that we can only be sure in such cases when we 

 can isolate the organism and reproduce the disease with the organism 

 so isolated, and it is not to his discredit that he was unable with the 

 methods then employed to do this. 



In our report to the Agricultural Experiment Station we say that we 

 regard treatment of individual cases as useless or worse than useless. 

 In regard to the prevention of the spread of the disease I can onlj? rec- 

 ommend the measures as advised in the report of the Bureau. 



There are still many interesting x)roblems in regard to the epizootic 

 diseases of swine which would reward investigation, but I have no doubt 

 that they will all be solved in time by the Bureau without any aid from 

 outside. 



I was unable to visit Kentucky, where my colleagues studied an out- 

 break. 



Very respectfully, 



B. Meade Bolton. 

 University of South Carolina, 



ColumUa, 8. (7., May, 1889. 



