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much confinement in fine weather and requires only to be regular & 

 moderate in the Diet. but observe that the drinking of Lignum vitae 

 Decoctions or using the gums of it prevent all the effects of mercury 

 for a considerable time so that giving these medecines to such for a 

 considerable time after the use of Lignum vitae will be ineffectual. Se to 

 such as have been lately salivated they must be given with the greatest 

 caution, for in such any preparation of mercury is apt to renew the 

 spiting. The Medecine is this. viz. Take Nine, 9, drachm. of Sarsa- 

 parilla reduced to a fme powder, four drachms of the purest crud mer- 

 cury, put them into a marble morter & ad as much water gradually as 

 will brink the powder into the consistance of pills, bolus® , or Electuary, 

 rubing it at the same time very well. In this like the other the mer- 

 cury will be soon incorporated & perfectly extinguished & then it may 

 be given to one scruple one a day or half a scruple twice a day for 3 

 or four days, then you augment the dose to half a drachm pr Diem 

 for 4 Days after w^ you may augment it to, 50, gr. or one drachm to 

 be used for a continuance, with a little light Decoction of Sarsaparilla, 

 untill the cure is perfect. Observe, dureing this course it is not un- 

 common to feel a soreness in the mouth & troath. then you are to 

 dröp the Medecine for one, 2, or, 3 days & the Symptom will vanish 

 without purge or any other medecine after which you proceed again 

 with the mercurial medecine & so {toties quoties) untill the cure is per- 

 fect, w^ is generally performed in about, 5, or, 6, weeks often in one 

 month. but in this also, the quantity of the Dose may be varied. some 

 require larger doses; tender persons, & those used to the taking of mer- 

 cury or such as have been salivated must not have the proportion of 

 mercury, they must have smaller doses & those more seldom & always 

 used with the Decoction of Sarsaparilla, w*^ other ways is not always, 

 no, nor often necessary. Would you, sir, expect the Sarsaparilla could 

 have so powerfull an effect of carriing mercury by the skin, I confess I 

 only hoped some assistance from it in the cure of the Yaws but the 

 effects of the composition have been so extraordinary, that I have after- 

 wards ordered it for some hundreds with perfect success, both in that 

 disease, for w^ before there was no perfect cure & in all appearances of 

 the venereal Disease. N. B. in incipient Buboes I have intermixt the use 

 of the first pills with rubarb, & chankres are made perfectly easy by the 

 following wash viz. R. Mercurii corrosivi sublim. 3 i. sp. vini rectificati 

 § i. fiat solutio perfecta in mortario vitreo: 8, or 10 dröps of this in 2 

 table spoonfulls of warm water, serves not only as a wash but but dipt 

 in the water also & layed to those burning sores his die soon clears 



