DISEASES OF THE OX AND SHEEP. 839 



In the course of scarlet fever, the conjunctivae notunfrequently 

 inflame, and occasionally in the second or third week of the 

 disease, the ophthalmia becomes intense and purulent, and slough- 

 ing of the corneee may result. Again, inflammation sometimes 

 extends along the eustachian tube to the tympanic cavity, pro- 

 ducing otitis, with possibly disease of the petrous bone, and, 

 meningitis, abscess of the brain, or pyeemia. Inflammation may 

 extend also to the nose and produce chronic catarrh of its 

 mucous surface. Inflammation of the pericardium or of the 

 pleurse (the latter often purulent) is not uncommon. During 

 the decline of the fever, or even during the period of convales- 

 cence, rheumatism may come on. To scarlatinal rheumatism, 

 which, it is said, diff"ers in no respect from ordinary rheumatism, 

 affections of the heart, and chorea or embolism occasionally 

 succeed. The most important complication, however, is nephritis, 

 which frequently comes on in the second or third week. As a 

 rule, this condition passes off without any ill result. Not un- 

 frequently, however, ureemia comes on, attended with severe 

 headache and convulsions, frequently ending in death. If 

 judicious treatment be resorted to, the albuminuria and the 

 dropsy may subside ; but at times the urine remains permanently 

 albuminous, and the kidneys undergo slow disorganization. 

 Anasarca sometimes remains after the disappearance of the 

 albuminuria, and it is said that this condition occasionally arises 

 in those patients who have never had albumen in the urine. 



Morbid Anatomy. — In malignant cases there may be col- 

 lapse and hypostatic congestion of the lungs, and haemorrhage 

 into and at the free surfaces of internal organs. The throat 

 generally presents distinct traces of inflammation and ulceration. 

 The solitary intestinal glands and Peyer's patches are somewhat 

 enlarged, and may be ulcerated. Ante-mortem clots are not 

 uncommon in the right ventricle. 



Dr. Klein has shown that even at the earliest stage of the 

 disease there is a marked tendency to inflammatory hypersemia 

 and proliferation, not only in the skin, mouth, throat, and 

 kidneys, but throughout the alimentary canal, and in the sali- 

 vary glands, pancreas, liver, lymphatic glands, and spleen. 

 Generally in all these parts there are observed germination of 

 the endothelium of the small blood-vessels, hyaline thickening 

 of the intima, germination of the nuclei in the muscular coat 



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