48 THE DISEASES OF DOMESTIC ANIMALS. 



and colon. These consisted of peculiar growths or ulcerous tumors 

 in the mucosa. (Whether these were limited to the Peyer's patches 

 or not the report does not say.) They varied in size and shape, and 

 were more or less prominent above the general surface of the mu- 

 cosa. The base of the older ones was frequently more or less pig- 

 mented. Their size varied from that of a pin's head to a quarter of 

 a dollar. The smaller ones were generally of a yellowish color, and 

 projected but slightly ; the larger ones were of a grayish-brown 

 color, or even blackish, and had usually a slight concavity in the 

 center. The greater part of these growths consisted of connective 

 tissue. In some cases these growi;hs, especially the smaller ones, 

 or those of recent origin, were situated upon the surface of the mu- 

 cosa, and were easily scraped off, leaving behind an uneven, excori- 

 ated surface, having the appearance of granulation tissue. The 

 older and larger tumors penetrated more deeply into the substance 

 of the mucosa — in some cases so deeply that their removal caused 

 perforation of the walls of the intestine. Similar productions were 

 also found in. other parts of the intestine. 



The contents of the gall-bladder were found, in many cases, to 

 consist of a semi-solid, granular, dirty-brownish substance. In most 

 of them the ductus choledochus appeared to be thickened, so that 

 the semi-solid condition of the bile might be attributed to absorption 

 of its fluid elements, due to retention. 



Morbid changes in the skin were frequently met with, consisting 

 of ulcers, purple spots or patches, or diffuse redness. 



The blood presented both qualitative and quantitative changes. 

 It was dirt-colored in all cases wdiere death had been caused by cxt 

 tensive pulmonary complications, but was thin and light-colored 

 where pathological changes predominated in other parts of the or- 

 ganism. It invariably coagulated on exposure to the atmosj)here. 

 The kidneys exhibited no very marked change. 



Microscopic Observations. (Law.) 



Skin. — Microscopic sections through the affected portions of the 

 skin showed the various grades of congestion, with blocking of the 

 capillaries, and an excess of lymphoid and large granular cells and 

 pigment granules with extravasations and necrotic centers. With 

 the earlier congestion there is more or less anasarca and consequent 

 separation of the elements of the cutis, while in the later or more 

 severe conditions a fibrinous exudation takes place, and this may 

 even exude upon the free surface and form dark scabs. In no in- 

 stance was formation of pus in the skin to be seen. One feature. 



