186 THE DISEASES OF DOMESTIC ANIMALS. 



becomes thicker, more viscid, of a queer yellowish-green color, and 

 adheres moi'e or less to the nostrils. 



These nodes and infiltrations soon begin to show evidences of 

 breaking down, the edges become swollen and ragged, resembling 

 rodent ulcers; they extend by the formation of new nodes, or pro- 

 liferations in the circumference, and the sequential breaking do%vn 

 of the same ; frequently such ulcei's coalesce, giving rise to extensive 

 ulcerated surfaces. When these conditions last a long while, perfo- 

 ration of the septum sometimes takes place. 



It has been noticed that the discharge is often limited to one 

 nostril, and particularly to the left, for which we have no explana- 

 tion, but, whichever side it is, there is the locality of the most serious 

 disturbances. 



The submaxillary and retro-pharyngeal lymph-glands soon be- 

 come complicated, the infectious elements gaining access to them 

 by means of the lymphatics of nasal cavities. The lymphatics may 

 often be seen as swollen cords, and, if not seen, felt. The processes 

 in the glands are essentially of an indurative character. The breath- 

 ing is frequently labored, from the complication of the larynx, so 

 much so that death may sometimes result from oedema glottidis. 

 The fever increases, the animals become more and more depressed, 

 lose their appetite, etc. If this condition appears as a conclusion 

 of chronic glanders, we have mucous rales in the bronchi, sometimes 

 pneumonic infiltration, with the usual respiratory symptoms. 



Soon follow oedematous swelling of the legs, sheath, the sub-ab- 

 dominal region, with the characteristic farcy-buds over difi'erent 

 parts of the body, especially the posterior, the swollen lymphatics, 

 the complications, induration of the sub-cutis, etc. "With tlie prog- 

 ress of the disease, and breaking down of the tissues, the discharge 

 from the nose and cutaneous ulcers becomes more profuse, diarrhoea 

 frequently sets in, albuminuria is present, and, if not killed, the 

 animals die a miserable death in from eight to fourteen days. 



In a case of chronic glanders, inflammatory conditions may be 

 ushered in by a variety of circumstances, viz. : an infected horse 

 may, in the same manner as a healthy one, be attacked by any 

 acute feverish disease, let it be from any mechanical injury, from 

 the influences of cold, or miasmata, or any such thing. Catarrhal 

 disturbances of the respiratory tract are especially favorable to the 

 transformation of chronic to acute glanders. Bad weather, cold and 

 dry east winds, in fact, any influences which tend to irritate the mu- 

 cosae, exert a similar influence. The same is true of severe surgical 

 operations, wounds, fever, etc. 



