142 DISEASES OF SWINE 



from the liver. This obstruction is sometimes quite marked and 

 accompanied by a genuine catarrhal jaundice, with discoloration 

 of the entire body, due to the absorption of coloring-matter from 

 the bile and deposit over the entire carcass. 



If an examination be made of a stained section of the liver under 

 the microscope it shows changes here very similar to those which 

 were found in the spleen, but not nearly so well marked or severe. 

 The individual liver cell is markedly swollen and stains poorly 

 with the laboratory stains. The nucleus of the cell is often frag- 

 mented, and quite a number of cells are found in each lobule which 

 show complete destruction. The blood-vessels at the center of 



Fig. 48. — Hog-cholera kidney, showing turkey-egg spotting. (Photo by Dr. 

 Geo. R. White.) 



and around the margin of the lobule are dilated and filled with 

 blood, with here and there a blood-clot or thrombus seen in the 

 blood-vessel. 



In some of the cases with high fever there is, in addition to 

 this parenchymatous degeneration, a well-pronounced fatty de- 

 generation of the liver. In these cases fat-droplets appear within 

 the cell, and the entire appearance of the liver is greasy and yel- 

 lowish, the cut surface often dripping an oily, fat-like fluid when 

 cut across with the knife. 



Changes in Kidneys. — It is in these organs that we find the 

 greatest uniformity of lesions and the most constant presence of 

 changes typical of the disease. There are no other organs in the 



