432 DISEASES OF SWINE 



untreated animals, leaves no question as to the deadly nature of 

 the disease. 



We must, therefore, conclude that in this instance the serum 

 proved of value not only as a prophylactic agent, but also, to 

 some extent, as a curative. 



While the advocates of the serum method of treatment have 

 never been strong in their arguments in favor of the use of serum 

 as a curative measure in cholera, and have contented themselves 

 with urging the use of the agent as a simple preventive, evidence 

 is constantly accumulating to show that serum, when properly 

 made, does possess quite appreciable curative properties, and the 

 results being obtained in various parts of the country justify its 

 use even in sick animals, unless the hogs are already in a dying 

 condition. 



During the time that I was engaged in the demonstration work 

 in Missouri we injected a number of swine which gave every evi- 

 dence of being infected at the time, and several of which mani- 

 fested high temperatures at the time of injection. Our results 

 in many of these cases exceeded expectations, and led me to the 

 conclusion that further experimentation with this agent will 

 establish for it a place in the rank of curative agents as well as 

 simple preventives. 



Herd Number Four. — This herd was located in the northwest 

 quarter of Section 11, Grant Township, Story County. When the 

 farm was first visited on September 25, 1907, the herd was appar- 

 ently well, although the disease had for some days been only 

 half a mile distant. The herd at this time consisted of 30 spring 

 shoats, each weighing from 75 to 100 pounds, and 3 old sows with 

 young litters. 



In planning the experiment the intention was to treat all of 

 the animals except the sucking pigs. In corraling the herd for 

 treatment, one of them escaped and could not be afterward 

 located. This animal, therefore, went untreated. Consequently, 

 29 shoats and 3 old sows were treated, the shoat which escaped 

 and the sucking pigs being left as checks. The method of treat- 

 ment here used was the double or serum-simultaneous method. 

 Each shoat received 20 c.c. of serum and 2 c.c. of virulent blood. 

 The old sows were each given 40 c.c. of serum and 2 c.c. of viru- 



