CLINICAL EVIDENCE OF VALUE OF SERUM 449 



ceived 10 c.c. each of serum alone. Three shoats, of an average 

 weight of about 90 pounds each, received 20 c.c. of serum with 1 c.c. 

 of virus blood. Five sows that had raised litters of pigs and, ac- 

 cordingly, were in somewhat poor flesh, each received an injection 

 of 30 c.c. of the same serum with an accompanying injection of 

 2 c.c. of virulent blood. Two 90-pound shoats and 8 small pigs 

 were left untreated, to serve as checks. 



Eleven days later the owner of this herd reported that 2 of the 

 animals which had been treated were off feed. A visit was made to 

 the farm on October 28th, and at this time one of the animals which 

 had seemed about to get sick was entirely recovered and the other 

 one seemed much better. At this time, however, a third shoat was 

 apparently becoming ill. In order to prevent a serious outbreak 

 of the disease most of the checks and a number of the previously 

 treated animals were given a second injection of serum alone, each 

 animal receiving 20 c.c. of serum. 



The balance of the report on these animals is not very definite, 

 and it is a little hard to determine just how much good the serum 

 did in this particular case. The final report on this herd shows that 

 one animal died, but as there was no opporunity to open up the 

 body and examine same after death, it is impossible to say whether 

 or not the hog died from cholera or some other condition. 



The report on this herd is lacking in the details that are neces- 

 sary to arrive at a correct conclusion as to the effects of the serum 

 treatment, but one important conclusion can be drawn even from 

 the incomplete information obtained in this case, and that is, 

 that results were very good. This herd was located in the midst 

 of a cholera outbreak, with cholera herds located all around it, 

 and yet passed through the outbreak with the loss of only one 

 animal, and that without it being positively shown that this death 

 was due to cholera. 



The fact that a few of these animals showed signs of getting 

 sick after the double treatment, and this, together with the fact 

 that the herd was treated on the same day as Herd Number Eleven, 

 would make it seem just possible that there was some undeter- 

 mined influence at work here which caused the unsatisfactory 

 results reported. 



In this herd we again have, however, an example of the fact 



