CLINICAL EVIDENCE OF VALUE OF SERUM 471 



sickness. It is, indeed, unfortunate that opportunity did not 

 allow for the making of a postmortem examination in the case 

 of the treated shoats that died of the disease, in order to deter- 

 mine definitely whether or not they really died from cholera. 

 From the circumstances surrounding the injection of this herd, 

 and the statement of the owner that the symptoms which they 

 showed were not those of hog-cholera, it would seem highly prob- 

 able that there was some other disease present in the herd which 

 accounted for the death of .these treated shoats. 



In this connection it must be remembered that while hog- 

 cholera serum, and especially the double method of treatment, 

 is a lifelong protection against hog-cholera, it is not a protection 

 against other diseases of the hog. Such diseases as pneumonia, 

 oil-meal poisoning, slop or brine poisoning, etc., may kill the ani- 

 mal even after he has been protected against hog-cholera by a 

 suitable injection of serum or serum and virus blood. 



Herd number twenty-one was located in the northeast quar- 

 ter of Section 25, Milford Township, Story County, Iowa. This 

 herd was located in an infected district, and hog-cholera was 

 present on a number of the farms in the immediate neighborhood. 

 This farm was first visited on October 18, 1907. At this time 

 the herd all appeared to be well and in good condition with the 

 exception of 2 or 3 pigs, which appeared to have some difficulty 

 in breathing. They showed very much the symptoms of what is 

 commonly known among farmers and stockmen as "thumps." 



On account of the fact that no previous arrangements had 

 been made with the owner regarding the administration of the 

 serum treatment, the animals were not in a close range and only 

 a small number of the herd could be treated. 



Eleven spring shoats, weighing about 125 pounds each, were 

 given 30 c.c. of the serum, with an accompanying injection of 

 2 c.c. of virulent blood. Nine other shoats, weighing on an aver- 

 age of 50 to 100 pounds, were also treated, each receiving 20 c.c. 

 of serum and a 2-c.c. dose of the virus blood. One old sow, weigh- 

 ing about 250 pounds, was given 40 c.c. of the serum and 2 c.c. 

 of virulent blood. 



On account of the fact just mentioned, that no previous 

 arrangements had been made for treatment of this herd, it 



