474 DISEASES OF SWINE 



30 pounds each, were given 20 c.c. of the serum and 1 c.c. of virus 

 blood. Thirteen small sucking pigs were injected with the serum 

 alone, receiving 10 c.c. each of serum. 



Within two or three days after the treatment some of the suck- 

 ing pigs began to show unthriftiness, loss of appetite, and other 

 signs of disease. Several of the smaller of these pigs finally died, 

 and, on being examined postmortem, showed the usual evidences 

 of hog-cholera, the dark-red spotting of the kidneys being quite 

 prominent. The shoat that was sick when treated finally died, 

 and another shoat, which did not appear to be sick at the time of 

 treatment, developed a marked swelling of the abdomen and 

 finally died. The balance of the herd suffered for some time with 

 a more or less troublesome cough, but none of them died. 



The fact that several of the pigs became sick within a day or 

 two after the administration of the treatment would indicate 

 that this herd was just beginning to come down with cholera at 

 the time of treatment, and the giving of the treatment unques- 

 tionably saved the lives of a large number of the animals. 



This herd gives a good example of what may be accomplished 

 in a herd where cholera is just starting by getting in at once with 

 properly prepared serum. The usual loss in a herd of this size from 

 an outbreak of cholera would have been at least 50 per cent, of 

 the herd. Here we have the loss of only a few of the sucking pigs, 

 one shoat that was quite sick at the time of treatment, and one 

 other shoat that probably died from some complication rather 

 than from the cholera attack itself. 



The pigs died, perhaps, because they were already badly in- 

 fected at the time, and also, perhaps, the dose of serum used was 

 a little small, considering the fact that they were already sick. 

 Sucking pigs require a larger dose in proportion to their weight 

 than the older animals. 



Herd Number Twenty-three. — The twenty-third experimental 

 herd reported in this series of test cases was located in the north- 

 west quarter of Section 32, Milford Township. This herd was in 

 an infected district, and at the time it was first visited there was 

 a cholera herd on another farm not over 40 rods distant. This 

 herd was first visited on October 21, 1907. At this time one shoat 

 was off feed, but was not sufficiently sick to warrant killing for 



