CLINICAL EVIDENCE OF VALUE OF SERUM 479 



ceived 20 c.c. each of the serum with 1 c.c. of virulent blood. 

 Twenty-one old sows were each given 40 c.c. of serum with 1 c.c. 

 of virus blood. Two old boars were each given 40 c.c. of the serum 

 with 1 c.c. of virulent blood. Ten small sucking pigs were injected 

 by the single or serum-alone method, each pig receiving 20 c.c. of 

 the serum. Ten young boars received 20 to 30 c.c. of serum with 

 1 c.c. of virus. Three gilts were left untreated for the purpose of 

 being exposed later along with some of the treated animals in case 

 the herd proved not to have been affected with hog-cholera at the 

 time of treatment. 



This herd was next visited on October 31st, and at this time a 

 number of the gilts, including the 3 checks, were sick. One old 

 sow died very soon after the treatment was given, but, in the 

 opinion of the owner, she had not shown the usual symptoms of 

 hog-cholera. According to his statement, she swelled badly under 

 the abdomen, and it is quite possible that she was infected with the 

 germs of blood-poisoning at the time of injection, and died from 

 this disease rather than from cholera. 



A postmortem examination at this time was made of one of the 

 sucking pigs, and the changes found were those of hog-cholera as 

 usually seen. There was some redness of the skin, the glands in 

 the flank were enlarged and reddened, the spleen was enlarged and 

 dark in color, the liver was congested, and there were several pin- 

 point red dots in the kidneys. 



On November 7th, when the next report was received on this 

 herd, nearly all of the sucking pigs, several of the gilts, and one 

 young boar had died. A few others were sick at this time. 



On November 24th another visit was made to this farm. At 

 this time 2 of the gilts had just died, and a postmortem examina- 

 tion was made of the dead bodies. In both cases the changes re- 

 ported are those usually seen in the acute type of hog-cholera — the 

 lungs were congested and filled with blood, the spleen was enlarged 

 and dark in color, the liver was much congested, there was a well- 

 marked spotting of the kidneys, and many small ulcers were found 

 in the large bowel. 



Another inspection of the herd later on showed that 16 gilts, 3 

 old sows, 3 boars, 9 of the sucking pigs, and 2 of the checks had died. 

 The third check had also become sick, but later recovered. 



