CLINICAL EVIDENCE OF VALUE OF SERUM 487 



The 2 treated shoats which died were no doubt already 

 coming down with the disease at the time that the treatment 

 was given, and, to have any beneficial effects in their case, it would 

 have been necessary to use a much larger dose of serum than was 

 here used. 



Herd Number Thirty-two. — This herd was located in the 

 southeast quarter of Section 18, Grant Township, Story County. 

 It was first seen and treated on October 24, 1907. These hogs 

 had already been exposed to hog-cholera, and some of the ani- 

 mals were at this time showing signs of illness. Two of the 

 shoats exhibited well-marked symptoms of hog-cholera — loss of 

 appetite, remained in their nests, appeared droopy, and were 

 weak in the hind extremities. The balance of the herd still ap- 

 peared to be well. 



Fourteen shoats, which were of an average weight of about 

 150 pounds each, received 30 c.c. of the serum plus 2 c.c. of the 

 virulent blood. Eight shoats of the same weight were each given 

 20 c.c. of serum and 2 c.c. of the virus blood. Twenty-one shoats, 

 including the 2 sick ones, ranging in weight from 40 to 100 pounds 

 each, received 20 c.c. of the serum plus 2 c.c. of the blood. Nine 

 shoats, which were slightly smaller in size, each received 20 c.c. 

 of the serum with 1 c.c. of the virus blood. One old sow weighing 

 250 pounds was given 40 c.c. of the serum and 2 c.c. of virulent 

 blood. 



Fourteen shoats, which averaged from 40 to 150 pounds, were 

 left untreated to remain as checks. 



When seen on November 5th the 2 pigs that were sick when 

 treated had died. The other treated pigs were all apparently well. 

 One of the check animals had died and 12 others were sick. The 

 checks continued to die, until 11 of the 14 were lost. One of the 

 3 which survived was rendered worthless by the disease and be- 

 came a chronic runt. The other 2 recovered and were in fairly 

 good condition. 



The result on this farm was very pleasing. The outbreak in the 

 herd was genuine cholera, and was of a fairly severe type, as evi- 

 denced by the death of all the check animals except 3. There can 

 be no question as to the beneficial results obtained in this herd 

 from the serum treatment. Not one of the treated animals was 



