CLINICAL EVIDENCE OF VALUE OF SERUM 501 



west quarter of Section 17, Grant Township. The owner had 

 noticed that the animals did not seem to be doing right for several 

 days. When visited by the government officials they showed loss 

 of appetite, and many of them appeared gaunt and unthrifty. 

 None of them were sufficiently sick, however, to justify killing 

 them for the purpose of making a postmortem diagnosis. 



In treating the herd the serum-alone treatment was used. 

 Fifty spring shoats, weighing from 125 to 200 pounds, were given 

 40 c.c. each. One smaller shoat received 20 c.c. of the same serum, 

 and another shoat was given 15 c.c. Fifty-three were left untreated 

 to serve as checks. 



The after-history of this herd showed that none of the treated 

 animals or checks died. The herd evidently was not suffering 

 from cholera. The experiment gives an illustration of the fact 

 that not every disease associated with loss of appetite and loss 

 of weight is cholera. This herd was more likely the victim of 

 indigestion, due to improper feeding or perhaps the presence of 

 intestinal parasites. The experiment does show that the injec- 

 tion of serum even in other diseases than cholera does no harm, 

 and it is a wise precaution to use the serum in any suspicious 

 cases, if there be a reasonable likelihood that cholera exists. 



Herd Number Forty-two. — This herd was located in Section 

 21, Franklin Township. There were no cholera-infected farms in 

 the immediate neighborhood of the premises. The herd was made 

 up entirely of pure-bred Chester-White hogs, and consisted of old 

 sows, young spring gilts, young boars, and a number of fall pigs. 



At the time the herd was examined and treated hog-cholera 

 had already made its appearance on the farm. This had been 

 brought on the farm by the importation of a breeding animal 

 from a distant part of the state. At the date of treatment one 

 boar had died, 2 others showed symptoms of hog-cholera, and 

 the majority of the herd had been exposed by contact with the 

 sick animals. 



In the treatment of these hogs 2 young boars, each weighing 

 about 175 pounds, received 50 c.c. each of serum. One old boar, 

 weighing about 700 pounds, was injected with 60 c.c. of serum. 

 Seventeen old sows, which averaged from 300 to 500 pounds in 

 weight, were each injected with 60 c.c. of serum. One old sow. 



