CLINICAL EVIDENCE OF VALUE OF SERUM 505 



not as brilliant a one as some that have been already shown, yet 

 it is a very good showing when it is taken into consideration that 

 almost every hog on the place was very sick at the time when the 

 treatment was given. In the case of the small pigs, I am of the 

 opinion that some of these might have been saved had the dose of 

 serum used been larger; 10 c.c. of serum is sufficient in very small 

 pigs to act as a protective dose, but where the cholera germs have 

 already begun their attack and visible symptoms of cholera are 

 present it would seem wise to give a considerably larger dose, even 

 to sucking pigs. 



This outbreak was unquestionably a virulent one, as shown by 

 the result in both treated and untreated animals, and it is doubtful 

 if more than 2 or 3 shoats would have survived if the serum had not 

 been used. The results here obtained should encourage stockmen 

 and veterinarians to make use of high-grade serum even after the 

 disease has made a good start. This is especially to be advised 

 where the herd consists of a number of pure-bred hogs, the saving 

 of one of which would more than repay for the cost of the serum 

 used in the entire herd. 



Herd Number Forty-five. — This herd was located in a somewhat 

 different locality from most of those already reported. The farm 

 on which these animals were kept was in the outskirts of Nevada, 

 Iowa. Hog-cholera had been raging in the surrounding neigh- 

 borhood for several weeks. Infection had already reached the 

 farm at the time the United States veterinarians visited the 

 premises, and many of the hogs were already visibly sick with 

 symptoms that were unquestionably those of genuine cholera. 



Four of the animals had already died at this time, and a num- 

 ber of the remaining shoats were off feed and showed marked signs 

 of the dread disease. One of the dead animals was opened and 

 the findings were those usually seen in an acute case of hog-cholera. 

 Here, again, was a herd that could not be regarded as favorable for 

 injection with serum, but as the owner was very anxious to try and 

 save some of his herd treatment was administered. 



Twenty-nine shoats, varying in size and weight, were injected, 

 each receiving 40 c.c. of serum. Three old hogs of large size were 

 each injected with 80 c.c. of serum. Thirteen of the shoats were 

 left untreated, to serve as checks. 



