272 Wound Infection; Suppuration 



occasionally found in a purely sapropbytic role in various 

 situations in the human economy. It has been found in the 

 saliva by Pansini, in sputum by Frisch, and in the sweat by 

 Eberth and Audanard. Abelous demonstrated its presence 

 in the stomach as a saprophyte. Its existence in suppurat- 

 ing wounds has long been known, and Koch early detected 

 its presence in tuberculous cavities, regarding it as an 

 organism incapable of playing any pathologic role. The 

 etiologic relation of the organism to certain cases of purulent 

 otitis media in children was pointed out by Martha, Mag- 

 giora and Gradenigo, Babes, Kossel, and others. H. C. 

 Ernst obtained it from a pericardial exudate during life. G. 

 Blumer demonstrated its presence in practically pure cul- 

 tures in a case of acute angina simulating diphtheria; 

 Jadkewitsch, B. Motz, and L/e Noir obtained the bacillus 

 in cases of urinary infection. The cases of Triboulet, 

 Karlinski, Oettinger, Ehlers, and Barker are interesting 

 instances of its role in cutaneous lesions. 



"In addition to these lesions, other morbid processes 

 have been associated in some cases with the bacillus of 

 blue pus, such as meningitis and oroncho-pneumonia by 

 Monnier ; diarrhea of infants by Neumann, Williams, Thier- 

 celin and Lesage, and other observers; dysentery by Cal- 

 mette and by Lartigau; and general infection by Ehlers, 

 Neumann, Oettinger, Karlinski, Monnier, Krannhals, Cal- 

 mette, Finkelstein, and L. F. Barker." 



Nine additional cases of human infection are reported by 

 Perkins.* 



Immunity. Immunity against pyocyaneus infection de- 

 velops after a few inoculations with attenuated or sterilized 

 cultures. These are easily prepared, the thermal death- 

 point determined by Sternberg being 56 C. 



MISCELLANEOUS ORGANISMS OF SUPPURATION DESCRIBED 

 MORE FULLY ELSEWHERE. 



Before leaving the subject of suppuration, attention must 

 be directed to other bacteria that under exceptional circum- 

 stances become the cause of suppuration. Among these are 

 the pneumococcus of Frankel and Weichselbaum, the typhoid 

 bacillus, Bacillus coli communis, and the Micrococcus tetra- 

 genus. These organisms are considered under separate and 

 appropriate headings, to which the reader is advised to refer. 

 * "Jour, of Med. Research," vol. vi, 1901, p. 281. 



