THE REPRODUCTIVE GLANDS. 447 



Sodium (Na 2 O) 23.56-32.93 



Potassium (K 2 O) 27.66-28.45 



Calcium (CaO) 1.74- 2.90 



Magnesium (MgO) 1.60- 3.17 



Iron (Fe 2 O 8 ) - 44 ~ - 55 



Chlorine (Cl) 23.84-28.56 



Phosphoric acid (P 2 O 5 ) 3.16- 4.83 



Carbonic acid (CO,) 9.67-11.60 



Sulphuric acid (S() 3 ) 1.32- 2.63 



Silicic acid (SiO 2 ) 0.28- 0.49 



Fluorine (Fl) '. traces 



Of these constituents, the large amount of sodium chloride is espe- 

 cially noteworthy, and shows in itself that the albumen is in reality 

 a secretory product, and does not represent a mere transudation from 

 the blood-plasma. 



One portion of the bases is in combination with the albumins of 

 the albumen, while the remainder exists in the form of sulphates, 

 phosphates, and notably carbonates. 



The slightly yellow color of albumen is referable to the presence 

 of a lipochrome, which can be demonstrated on spectroscopic exam- 

 ination. 



The Albumins. According to Gautier and some of the older 

 observers, white of egg (albumen) contains a number of different 

 albumins, which in part seem to belong to the true albumins and in 

 part to the globulins. They have been designated as a-, /?-, and 

 f-ovalbumin, and - and /9-ovoglobulin. In so far as the globulin 

 fraction is concerned, Langstein has recently shown that it consists 

 of two portions, one of which after precipitation with ammonium 

 sulphate is insoluble in dilute saline solution, while the other dis- 

 solves. This latter fraction was further subdivided by salting with 

 potassium acetate into an euglobulin and a second fraction which can 

 subsequently no longer be precipitated by half-saturation with 

 ammonium sulphate. The euglobulin represents about two-thirds 

 of the total globulin fraction. 



The greater portion of the white of egg does not belong to the 

 globulins, and can be obtained in crystalline form, viz., the oval- 

 bumin proper. In addition we find a fraction which is not crystal- 

 lizable the so-called conalbumin of Osborne and Campbell, and 

 finally the ovomucoid of Morner. 



Globulin Fraction. The euglobulin above mentioned gives the 

 biuret reaction, the xanthoproteic reaction, that of Millon, Adam- 

 kiewicz, and markedly also that of Molisch. It is precipitated, on 

 dialysis, by a current of carbon dioxide, and on careful addition of 

 dilute acetic acid. It is soluble in an excess of acids and in dilute 

 saline solution, but readily passes over into an insoluble modification. 

 In a 2 per cent, solution it coagulates between 64 and 67 CX 

 Elementary analysis gave the following results : C = 49.88 ; H = 

 7.09 ; N ==14.36 ; S == 1.73 ; O = 26.92 (Langstein). On hydrol- 

 ysis with dilute hydrochloric acid it yields 11 per cent, of gluco- 

 samin. 



